北京男男性接触人群性传播感染HIV/HBV现状及相关因素研究

目的 探讨在北京男男性接触人群（men who have sex with men，MSM）人群中艾滋病病毒（human immunodeficiency virus，HIV）及乙型肝炎病毒（hepatitis B virus，HBV）的感染现状及相关高危因素，为疾病防控措施提供科学依据。方法 采用横断面调查，对北京MSM人群的社会人口学特征、高危性行为、相关病史等进行问卷调查，同时采集血样进行HIV、HBV及梅毒检测。采用Epi Data 3.0 软件建立数据库，利用SPSS 13.0统计软件进行统计分析。结果 MSM人群的HIV抗体阳性率11.6%，乙肝表面抗原阳性率为9.0%，出现乙肝病毒感染标志物占26.5%。多因素分析显示，较大的年龄、性伴不固定、无保护肛交、梅毒感染是HIV感染的独立相关因素；性伴不固定、有性病史是乙肝感染的独立相关因素。结论 北京男男性接触人群有着较高的HIV及HBV感染流行率，应加强对该人群进行HIV和HBV防护知识宣传、限制性伴数量，控制梅毒现症感染可以有效控制HIV及HBV感染的进一步蔓延。

Prevalence of and associated factors for HIV and HBV infections among men who have sex with men in Beijing,China

Objective To investigate the prevalence of human immunodeficiency virus （HIV） and hepatitis B virus （HBV） infection among men who have sex with men （MSM） population in Beijing and related high risk factors, and provide scientific evidence for disease prevention. Methods A cross-sectional survey was conducted in Beijing. A questionnaire was used to collect demographic information and potential correlated factors, and blood specimens were collected and tested for serologic markers of HBV, HIV and syphilis infections. Questionnaire-based data and serological testing results were recorded with EpiData 3.0 software. Statistical analyses were performed using SPSS 13.0. Results The prevalence of HIV and HBsAg were 11.6% and 9.0% , respectively. There are 26.5% had serologic markers of HBV infection. In multivariate analyses, two variables were independently associated with HBV infection： not having fixed male sex partners in the past 12 months, reported a diagnosis of a sexually transmitted disease （STD）. Multivariate analysis using forward stepwise Logistic regression confirmed that age, native place, not having fixed male sex partners in the past 12 months, unprotected anal intercourse in the past 12 months, syphilis rapid plasma regain （RPR） results were independent predictors of HIV infection. Conclusion High prevalence of HIV and HBV infection were observed among MSM. Comprehensive preventive measures for HIV and HBV and targeted health education campaigns should be developed among MSM population. The prevention and control of HIV and syphilis should be carried out simultaneously.