Use of deoxyribose by intestinal and extraintestinal pathogenic Escherichia coli strains: a metabolic adaptation involved in competitiveness |
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| Authors: | Bernier-Fébreau Christine du Merle Laurence Turlin Evelyne Labas Valérie Ordonez Juana Gilles Anne-Marie Le Bouguénec Chantal |
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| Affiliation: | Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France. |
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| Abstract: | We showed that the deoK operon, which confers the ability to use deoxyribose as a carbon source, is more common among pathogenic than commensal Escherichia coli strains. The expression of the deoK operon increases the competitiveness of clinical isolates, suggesting that this biochemical characteristic plays a role in host infectivity. |
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