表里双解法对急性湿疹患者血清IgE的影响

目的通过采用表里双解法对急性湿疹患者的治疗,以及对治疗前后血清IgE变化的观察,探讨刘完素六气怫郁化热理论在急性湿疹治疗中的运用。方法采用随机数字表法和相互对照设计方法,选取急性湿疹患者分成观察组和对照组各80例。观察组采用表里双解法治疗,方选防风通圣丸口服;对照组以3%硼酸溶液湿敷、炉甘石洗剂外搽以及安抚类乳剂外用治疗两周。两组患者治疗前及治疗1个疗程后分别取静脉血5ml,采用酶联免疫吸附法作血清IgE含量测定。结果观察组77例、对照组58例完成观察与随访过程。总有效率观察组为84.42%;对照组为51.72%。血清IgE治疗前观察组与对照组无明显差异(P>0.05),治疗后观察组明显较对照组低(P<0.05);治疗后对照组与治疗前无明显差异(P>0.05),观察组明显较治疗前低(P<0.05)。结论表里双解治疗急性湿疹可能与调节机体免疫功能有关;将刘氏的表里双解法运用于急性湿疹可以体“现火郁发之”法对“湿疮”的辨证论治的重要意义。

Effects of Exterior-Interior-Releasing Therapy on IgE in Acute Eczema Patients

Objective To observe the clinical efficacy of exterior-interior-releasing therapy on IgE in patients with acute eczema. Methods Seventy-seven cases in treatment group were treated by "Fangfeng Tongsheng Powder" and 58 cases in control group were externally treated by 3% boric acid, Luganshi lotion and other emulsion, with a course of 2 weeks. The content of IgE was detected. Results The total effective rate was 84.82% in treatment group and 51.7% in control group; after treatment, IgE decreased obviously in treatment group(P < 0.05), more significantly in treatment group than in control group(P < 0.05). Conclusion This therapy acts to regulate body immunity in the treatment of acute eczema.