Factors affecting quality of life in Hungarian adults with epilepsy: A comparison of four psychiatric instruments |
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| Affiliation: | 1. National University of Public Service, Budapest, Hungary;2. Károli Gáspár University, Faculty of Humanities, Institute of Psychology, Budapest, Hungary;3. Institute of Experimental Medicine, Budapest, Hungary;4. Pediatric and Adult Epilepsy–Neurology Centre, Budapest, Hungary;5. University of Szeged, Department of Clinical and Health Psychology, Institute of Psychology, Szeged, Hungary;6. National Institute of Clinical Neurosciences, Budapest, Hungary;7. Neurocenter, Rigshospitalet, Copenhagen University, Denmark;8. Szent János Hospital of the Municipality of Budapest, United Hospitals of North Buda, Department of Neurology, Budapest, Hungary;9. Szent János Hospital of the Municipality of Budapest, United Hospitals of North Buda, Department of Psychiatry and Psychiatric Rehabilitation, Budapest, Hungary;1. Department of Neurology and Institute of Health Science, Gyeongsang National University School of Medicine, JinJu, Republic of Korea;2. Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea;1. Department of Pharmacology, AIIMS, New Delhi, India;2. Department of Neurology, AIIMS, New Delhi, India;1. Department of Public Health & Policy, University of Liverpool, Liverpool, UK;2. Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, UK |
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| Abstract: | PurposeWe investigated the impact of 19 factors on life quality in Hungarian patients with epilepsy. Wellbeing was evaluated by several inventories to investigate the impact of factors in more detail.MethodsA cross-sectional study was performed in 170 patients. Wellbeing was evaluated with the WHO-5 Well-being Index (WHOQOL-5), Diener Satisfaction with Life Scale (SwLS), and the Quality of Life in Epilepsy-31 Questionnaire (Qolie-31). We investigated their association with demographic characteristics, general health status, epilepsy, and its treatment. The impact of these factors on illness perception (Illness Perception Questionnaire, IPQ) was also studied.ResultsThe four measures correlated highly significantly. In addition, the predictive power of factors was comparable with the four inventories as evaluated by Multiple Regression. Factors explained 52%, 41%, 63% and 46% in the variance of WHOQOL-5, SwLS, Qolie-31, and IPQ scores, respectively. However, associations with particular factors were instrument-specific. The WHOQOL-5 was associated with factors indicative of general health. SwLS scores were associated with health-related and several demographic factors. Neither showed associations with epilepsy-related factors. All four categories of factors were associated with Qolie-31 and IPQ scores. Factors had an additive impact on IPQ, but not on Qolie-31.SignificanceOur findings reveal interactions between the method of life quality assessment and the factors that are identified as influencing life quality. This appears to be the first study that analyses the factors that influence illness perception in epilepsy patients, and suggests that the IPQ may become a valuable tool in epilepsy research. |
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