Treatment of Epithelioid angiosarcoma with Topical ALA-PDT in the course of surgery |
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| Affiliation: | 1. Department of Orthopedics, Shanghai Tenth People''s Hospital, Tongji University School of Medicine, Shanghai 200072, China;2. Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China;3. The Advanced Institute of Translational Medicine, Tongji University, Shanghai 200092, China;4. School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | BackgroundEpithelioid angiosarcoma is a high grade malignancy sarcoma of soft tissue, which is hard to diagnose and completely excise without causing functional and cosmetic problems. Moreover, the high rate of recurrence is hard to salvage. Photodynamic therapy is a novel treatment protocol which can selectively destroy tumor cell with good functional and cosmetic outcomes.MethodsThis is a case about a 81 years old patient with Epithelioid angiosarcoma in the right medial angle of eye, which received surgery and ALA photodynamic therapy.ResultsThere is no recurrence in one year after treatment of surgery and photodynamic therapy in the course of surgery.ConclusionsExcision combined with photodynamic therapy during operation is a promising strategy towards tumors which are hard to resect thoroughly and have a high risk of recurrence. |
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| Keywords: | Topical photodynamic therapy Aminolevulinic acid Epithelioid angiosarcoma Therapy Surgery |
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