| 男性雌激素与骨代谢 |
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| 引用本文： | 甘卫东,戴玉田,孙则禹. 男性雌激素与骨代谢[J]. 中华男科学杂志, 2003, 9(1): 64-66 |
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| 作者姓名： | 甘卫东 戴玉田 孙则禹 |
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| 作者单位： | 南京大学医学院附属鼓楼医院泌尿外科,江苏,南京,210008 |
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| 摘 要： | 男性体内的雄激素可经芳香化酶作用转化为雌激素。成骨细胞具有雌激素受体 ,男性骨骼也是雌激素作用的重要靶器官。动物实验和临床研究均证实 ,芳香化酶缺乏或雌激素受体基因突变的男性 ,均可发生骨量减少 ,并形成骨质疏松。雌激素对男性骨骼的生长发育和骨量的保持发挥重要的作用
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| 关 键 词： | 雌激素 骨代谢 男性 |
| 文章编号： | 1009-3591(2003)01-0064-03 |
| 修稿时间： | 2002-03-19 |
Estrogen and Bone Metabolism in Man |
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| Wei Dong GAN,Yu Tian DAI,Ze Yu SUN. Estrogen and Bone Metabolism in Man[J]. National journal of andrology, 2003, 9(1): 64-66 |
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| Authors: | Wei Dong GAN Yu Tian DAI Ze Yu SUN |
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| Affiliation: | Department of Urology, Affiliated Drum Tower Hospital of Medical College of Nanjing University, Nanjing, Jiangsu 210008, China. |
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| Abstract: | In males, androgen can be aromatized into estrogen by aromatase. Estrogen receptors were shown to be present in male derived human osteoblasts. For males bone is an important target tissue of estrogen. It was demonstrated that deficiency of estrogen or mutation of estrogen receptor gene in males could lead to osteopenia, even osteoporosis. Estrogens are required for the pubertal growth of bone and play important roles in maintenance of bone mass in males. Natl J Androl,2003,9(1):64 66 |
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| Keywords: | Estrogen,Bone metabolism,Man Re cognition to the Physiological Functions of the Prostrate --The " Male uterus " in Traditional Chinese Medicine$$$$ Yun Feng QIN (Department of Male Infertity, Xuzhou TCM Hospital, Xuzhou, Jiangsu 221 |
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