胰岛素泵治疗56例糖尿病酮症酸中毒的疗效观察

目的：探讨胰岛素泵在糖尿病酮症酸中毒（DKA）治疗中的作用和疗效。方法：56例DKA患者随机分为胰岛素泵皮下输注胰岛素（CSⅡ）治疗组（29例）和对照组（27例），分别观察两组血糖达标时间、尿酮体转阴时间、pH值、胰岛素用量、低血糖的发生率。结果：CSⅡ组血糖达标时间、尿酮体转阴时间较对照组明显缩短（P〈0．01），胰岛素用量少于对照组（P〈0．05），CSⅡ低血糖发生率明显降低（P〈0．01）。结论：CSⅡ治疗DKA较小剂量胰岛素持续静脉治疗更安全有效。

Clinical observation of the effectiveness of insulin pump for the treatment of diabetic ketoacidosis in 56 patients

Objective: To investigate the usefulness and effectiveness of insulin pump for the treatment of Diabetic ketoaci-dosis (DKA). Methods: 56 patients with DKA were randomized divided into 2 groups, the treatment of subcutaneous in-sulin pump(CS Ⅱ ) with 29 patients and the control group with 27 patients. Observed the time to reach normal blood glucose level, the time to obtain negative results of urine ketone body, pH value, dose of insulin, incidence of hypoglycemia. Results: The CS Ⅱ group showed significantly decreased time to reach normal blood glucose level, and the time to obtain negative re-sult of urine ketone body, P<0.01. The CS Ⅱ group required lower dose of insulin (P<0.05) and had lower incidence of hypo-glycemia(P<0.01) than the ccontrol group. Conclusion: The CS Ⅱ is safer and more effective than conventional treatment.