| 感染性休克大鼠心肌肌浆网摄钙功能的变化 |
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| 引用本文： | 周雷,吴立玲.感染性休克大鼠心肌肌浆网摄钙功能的变化[J].基础医学与临床,1993,13(2):32-35. |
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| 作者姓名： | 周雷 吴立玲 |
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| 作者单位： | 北京医科大学病理生理教研室，北京医科大学病理生理教研室，北京医科大学病理生理教研室，北京医科大学病理生理教研室，北京医科大学病理生理教研室 北京，100083，北京，100083，北京，100083，北京，100083，北京，100083 |
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| 摘 要： | 本工作观察大鼠感染性休克不同阶段心肌肌浆网(SR)摄钙功能的改变。结果表明在休克早期心肌SR的钙摄取功能尚无明显变化;SR Ca~(2+)-ATP酶活性抑制和钙摄取量降低出现在感染性休克的晚期阶段,可能是心功能障碍的重要原因。
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| 关 键 词： | 感染性 休克 心肌 肌浆网 钙摄取 |
Alteration in Calcium Uptake by Cardiac Sarcoplasmic Reticulum in Septic Shock Rats |
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| Zhou Lei Wu Liling Qi Ying Tang Chaoshu Su Jingyi.Alteration in Calcium Uptake by Cardiac Sarcoplasmic Reticulum in Septic Shock Rats[J].Basic Medical Sciences and Clinics,1993,13(2):32-35. |
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| Authors: | Zhou Lei Wu Liling Qi Ying Tang Chaoshu Su Jingyi |
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| Institution: | Department of Pathophysiology Beijing Medical University |
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| Abstract: | Alterations in the ATP-dependent Ca2+ uptake by cardiac sarcoplasmic reticulum (SR) in septic rats were studied. The results show that calcium transport by cardiac SR was similar compared with sham-shock rats in early sepsis. The activity of Ca2+ -ATPase and Ca2+ uptake by SR were decreased significantly in late septic shock. It may play an important role for myocardial dysfunction in late septic shock. |
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| Keywords: | septic stock cardiac sarcopltsmic raticulum Ca2+-ATPase Ca2+uptake |
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