女性原发性腹膜癌27例临床及病理分析

目的：探讨原发性腹膜癌（PPC）的临床特点、诊断标准、治疗方法和预后。方法：对1993年1月－2000年12月在本院治疗的27例PPC患者的临床资料进行回顾性分析，其结果均经病理检查证实。结果：27例中，浆液性乳头状腺癌21例，粘液性乳头状腺癌4例，子宫内膜样癌1例，低分化癌1例。全部病例均施行肿瘤细胞减灭术，术后予以铂类为主方案的化疗。27例中3例失访，余24例中位生存期为28个月。结论：PPC原发于腹膜，是一种起病隐袭、发病率较低的疾病。应重视其术前诊断及鉴别诊断，减少误诊率。对PPC采取肿瘤细胞减灭术及铂类的主方案的化疗可显著改善预后，延长生存期。

Clinical and Pathological Analysis on 27 Cases of Female Primary Peritoneal Carcinoma

Objective:To investigate the clinical features,diagnostic criterion,treatment and prognosis of female primary peritoneal carcinoma (PPC).Methods:Twenty-seven cases of histologically confirmed PPC cases treated in our hospital from1993to2000were retrospectively analysed.Results:In this series,21cases were proved as serous papillary adenocarcinoma and the remaining cases were mucous(4cases),endometrioid(1case)and low differentiated carcino-ma (1case).All patients were given cytoreductive surgery and platin-based chemotherapy.Twenty-four patients were followed up and the median survival time reached28months.Con-clusion:PPC is a rare tumor.The initial definite diagnosis is difficult and the attention should be paid to differential diagnosis.The new diagnostic criterion of PPC is mentioned in this arti-cle.Long time survival can be achieved in some patients by cytoreductive surgery and platin-based chemotherapy.