血脂康对冠心病二级预防的作用

目的:探讨服用血脂康对中国人群冠心病二级预防的效果.方法:随机双盲法把100例心肌梗死后的冠心病患者分为血脂康研究组及安慰剂对照组,观察3～5年血脂变化、临床理化指标及冠心病事件、冠心病死亡、总死亡及对冠脉内支架术(PTCA)、冠脉旁路移植术(CABG)的需求量.结果:血脂康组调脂治疗后明显降低代17%,降低LDL-C29%,降低TG 7%,提高HDL-C 8%;同时临床终点事件明显改观,再发冠心病事件减少15.6%,冠心病死亡减少7.7%,总死亡减少9.6%,PTCA及CABG需求减少25.5%,且未见较明显不良反应.结论:血脂康对中国人群中的冠心病二级预防有肯定作用,副作用轻微.

Secondary Prevention Effect of Xuezhikang on Coronary Heart Disease

Objective: To explore the Secondary prevention effect of Xuezhikang(XZK) on coronary heart disease(CHD). Meth-ods: One hundred patients with CHD after myocardial infarction were divided in random double--blind way into groups: XZK treat-ment and placebo control. The following parameters were monirored within 3 to 5 yeare: blood lipid levels, Clinical manifestation, CHDevents, CHD--related death, total death rate, and requirement for percutaneous coronary artery (PTCA) and stent or coronary artory bypass graft (CABG). Results: After XZK treatment, TC decreased by 17%, IDL--C 29% and TG 7%, and HDL--C increased by8%. The difference of treatment effects between two group was significant. Recurrent CHD events decreased by 15. 6%, CHD--relateddeath 7. 7%, total death rate 9. 6%, and equirment for PTCA and CABG 25. 5% in XZK treatment group. XZK tretment had no obviousadverse effect. Conclusion: XZK is of secondry prevention effect on CHD in China population, and its adverse effects appear mildLy.