农村居民脑卒中危险因素及其交互作用研究

目的 探讨农村居民脑卒中的危险因素及其交互作用对脑卒中发病的影响.方法 采用以人群为基础的病例-对照研究方法,随机选择患者232人,健康对照232人进行调查.应用检验和Logistic回归分析脑卒中危险因素,应用相加效应模型分析脑卒中危险因素与家族史的交互作用.结果 长时间精神压抑、月经不规律和家族史是脑卒中的重要危险因素,其OR值分别为1 943、3.698和2.473；长时间精神压抑、月经不规律与家族史在脑卒中发病中存在交互作用,交互作用指数分别为1.656和6.034;交互作用归因危险比分别29.2％和79.6％；交互作用相对超额危险度分别为1.118和2.504.结论 长时间精神压抑、月经不规律和家族史是脑卒中的重要危险因素,而且长时间精神压抑和月经不规律与家族史之间存在正交互作用.

Risk factors of stroke and their interactions in rural residents

【Objective】 To explore the risk factors of stroke and their interactions in rural residents.【Methods】 With the method of population-based case-control study,we randomly selected 232 cases and 232 controls.Using testing and Logistic regression to analyze the risk factors of stroke,and to analyze the interactions with additive effects model.【Results】 Long-time psychological repression,irregular menstruation and family history of stroke are the important risk factors of stroke,OR is 1.943,3.698 and 2.473,respectively.Long-time psychological repression and irregular menstruation have a positive interaction with family history of stroke,S is 1.656 and 6.034,API is 29.2% and 79.6%,RERI is 1.118 and 6.034,respectively.【Conclusion】 Long-time psychological repression,irregular menstruation and family history of stroke are the important risk factors of stroke,long-time psychological repression and irregular menstruation have an positive interaction with family history.