小儿止泻片的药理研究

小儿止泻片系由多味中草药经现代科学方法精制的复方制剂。具有健脾剩水、和胃、补气止泻及消炎等功能。药理研究表明,对大鼠、豚鼠的离体胃底条及肠段自主运动均有显著性抑制作用,并对乙酰胆碱、氯化钡及组胺引起的十二指肠、回肠及结肠的痉挛性收缩有明显拮抗与阻断作用。能减低胃肠道推进机能,又能明显提高机体巨噬细胞的吞噬功能。

Pharmacological Study on Xiaoerzhixie Tablets

Xiaoerzhixie Tablets, composed of many species of Chinese herb medicines, is a compound preparation fined by modern scientific method. it possesses the effects of invigorating spleen and promoting diuresis, regulating stomach-energy, invigorating vital energy, stopping loose bowels and anti-inflam-mation. In the pharmaclolgical study, this Chinse papent medicine was found thai inhibition of anto nomic motion of strips of fundus ventriculi and pieces of intestine separated from rat and guinea pig was obvious. The study also revealed its striking antagonism and bloeking effects on the spastic contraction of duodenum, ileum and colon, induced by acetyleholine, barium chloride and histamine. Not only can it reduce the gastrointestinal drive function but remarkablely raise the phagocytosis of macrophage in body.