女性泌尿生殖道炎症样性病病人支原体检测及药敏试验

目的 :了解支原体在女性性病病人中的感染现状及耐药情况。方法 :应用淋球菌血琼脂培养基以及支原体鉴定定量和药敏试条对 6 5 17例拟诊性病病人取材做淋球菌、支原体培养和药敏试验。结果 :在拟诊性病病人中 ,病原体阳性率达 4 5 .2 8%(2 95 1/ 6 5 17) ,其中淋球菌占总阳性率 3.5 9%(10 6 / 2 95 1) ,沙眼衣原体 (Ct)占 5 8.4 9% (172 6 /2 95 1) ,解脲支原体 (Uu)占 79.30 % (2 340 / 2 95 1) ,人型支原体 (Mh)占 8.4 0 % (2 4 8/ 2 95 1) ,Uu +Mh阳性率 5 .79% (171/ 2 95 1) ;药物耐药情况依次为氧氟沙星 (5 4.32 % )、红霉素 (38.6 8% )、交沙霉素(32 .10 % )、多西环素 (2 4 .6 9% )、四环素(2 0 .16 % )和普那霉素 (11.93% )。结论 :泌尿生殖道炎症样的女性性病中以Uu感染为主。年龄以2 1～ 4 0a为主。支原体感染的耐药情况严重 ,在临床工作中同时进行支原体培养和药敏试验对临床用药具有重要意义。

Study of mycoplasma infection and drug susceptibility testing in female venereal patients with manifestation of genitourinary tract infection

AIM: To observe the infection and drug resistance of mycoplasma in female venereal patients. METHODS: Neisseria gonorrhoeae culture,mycoplasma culture and drug susceptisility testing were conducted to the samples of 6517 patients who were suspected of venereal diseases. RESULTS: In these patients,the positive rate of pathogen was 45.28 % ( 2 951 / 6 517 ). Among them,the proportion of neisseria gonorrhoeae,chlamydi trachomatis(Ct),ureaplasma urtalyticum (Uu),mycoplasma hominis(Mh) and Uu confirmed with Mh was 3.59 % (106/ 2 951 ), 58.49 % ( 1 726 /2 951), 79.30 % ( 2 340 / 2 951 ), 8.40 % (248/2 951) and 5.79 % (171/ 2 951 ),respectively. The results of drug susceptibility testing indicated that drug resistance of ofloxacine, erythromycine, josamycine, doxycycline, tetracycline and pristinamycine were 54.32 %, 38.68 %, 32.10 %, 24.69 %, 20.16 % and 11.93 % . CONCLUSION: In female venereal patients with manifestation of genitourinary tract infection, Uu is the major pathogen. Most of venereal patients are between 21 a and 40 a . Drug resistance of mycoplasma is severe. Culture and drug susceptibility testing of mycoplasma are important for clinical therapy.