脂质体载药系统与抗肿瘤药物

目的:介绍脂质体载药系统在抗肿瘤药物治疗中的应用.方法:采用文献综述方法,主要介绍普通脂质体和一些经过修饰后的脂质体作为药物载体的研究情况.结果:脂质体作为抗肿瘤药物的载体是可行的,可显著降低抗肿瘤药物的毒副作用,增加血药浓度并延长作用时间,还可明显提高抗肿瘤药物作用的靶向性.结论:脂质体是抗肿瘤药物的理想载体,在抗肿瘤治疗中有广泛的应用前景.

Liposome and Antitumor Drug Therapy

Objective:To review the research progress of liposome on antitumor therapy as a novel class of drug carriers.Methods:Researches of common liposomes and modified liposomes were reviewed in recent years at home and abroad.Results:It is feasible to select liposome as the drug carrier of antitumor drugs.It can greatly decrease the toxicity,increasing blood concentration after administration,and also develop the targeting effect of the encapsulated drugs.Conclusion:Liposome is an ideal carrier of antitumor drugs.It has extensive prospect in antitumor therapy.