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IL-35研究进展
引用本文:刘芬,文丽君,刘海燕. IL-35研究进展[J]. 免疫学杂志, 2011, 0(7): 630-632
作者姓名:刘芬  文丽君  刘海燕
作者单位:苏州大学医学部肿瘤细胞与分子免疫实验室;
摘    要:细胞因子在介导机体针对病原微生物的免疫反应、自身免疫耐受以及维持机体内环境平衡等过程中起了重要作用,IL-35是最近几年新发现的细胞因子,属于IL-12细胞因子家族,对免疫系统和免疫反应有负向抑制作用。本文对这一新细胞因子生物学特性的研究现状作一综述。

关 键 词:IL-35  Tregs  细胞因子

Progress of IL-35 studies
LIU Fen,WEN Lijun,LIU HaiyanLaboratory of Tumor Cell , Molecule Immunology,Medical College of Soochow University,Soochow University,Suzhou ,China. Progress of IL-35 studies[J]. Immunological Journal, 2011, 0(7): 630-632
Authors:LIU Fen  WEN Lijun  LIU HaiyanLaboratory of Tumor Cell    Molecule Immunology  Medical College of Soochow University  Soochow University  Suzhou   China
Affiliation:LIU Fen,WEN Lijun,LIU HaiyanLaboratory of Tumor Cell and Molecule Immunology,Medical College of Soochow University,Soochow University,Suzhou 215123,China
Abstract:Cytokines play an important role in mediating the body's immune response to pathogenic microorganisms,maintaining tolerance to self-antigens and the immunological balance of the body.A newly identified cytokine,IL-35,is one of the IL-12 cytokine family,and has inhibitive effects on immune system and immune responses.In this review,the recent studies on the biological characteristics of IL-35 are briefly reviewed.
Keywords:IL-35  Tregs  Cytokines  
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