首页 | 本学科首页   官方微博 | 高级检索  
     

类风湿关节炎患者抗环瓜氨酸肽、角质蛋白抗体和类风湿因子相关性探讨
引用本文:陈绩才,林秋强,陈韧,林玉英. 类风湿关节炎患者抗环瓜氨酸肽、角质蛋白抗体和类风湿因子相关性探讨[J]. 中国实用医药, 2010, 5(19): 1-2
作者姓名:陈绩才  林秋强  陈韧  林玉英
作者单位:1. 广东省汕头市澄海人民医院检验科,515800
2. 广东省汕头市澄海人民医院风湿科,515800
摘    要:目的对类风湿性关节炎患者血清抗环瓜氨酸肽(CCP)、角质蛋白抗体(AKA)和类风湿因子(RF)进行检测,并对这些抗体间相关性进行探讨。方法采用酶免疫法检测抗环瓜氨酸肽抗体;间接免疫荧光法(IIF)检测AKA;采用乳胶凝集法检测RF;采用卡方检验对结果进行统计学比较。结果RA患者血清中抗CCP阳性率83.3%(75/90),AKA(1:10)阳性率44.4%(40/90),RF(1:20)阳性率66.7%(60/90)。结论虽然RA患者血清中可出现上述三种抗体,但AKA与抗CCP、AKA与RF之间无相关性,而抗CCP与RF之间有相关性。

关 键 词:类风湿关节炎  抗环瓜氨酸肽  角质蛋白抗体  类风湿因子

Discussion on Correlation between Cyclic Citrullinated Peptid, Antikeratin antibody, and Rheumatoid Factor in Patients with Rheumatoid Arthritis
Affiliation:CHEN Ji-cai,LIN Qiu-qiang, CHEN Ren, et al. (The People' s Hospital of Chenghai, Chenghai, Guangdong Province, Chenghai 515800, China)
Abstract:Objective Subjectiue Thisstudy isto detect the cyclic citrullinatedpeptid( CCP) ,antikeratin antibody( AKA) ,and rheumatoid factor( RF) of the serum of patients with rheumatoid arthritis,and to discuss the correlation between these three antibodies.Methods The study applied the enzyme immunoassay for the detection of cyclic citrullinated peptid( CCP) ;applied the indirect immunofluorescence( IIF) for the detection of antikeratin antibody( AKA) ;applied the latex agglutination for the detection of rheumatoid...
Keywords:Rheumatoid arthritis  Cyclic citrullinated peptid  Antikeratin antibody  Rheumatoid factor  
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号