Mapping thyrotropin β subunit gene in man and mouse |
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| Authors: | S L Naylor A Y Sakaguchi L McDonald S Todd P A Lalley T B Shows W W Chin |
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| Institution: | (1) Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 78284 San Antonio, Texas;(2) Institute for Medical Research, 05201 Bennington, Vermont;(3) Roswell Park Memorial Institute, 14263 Buffalo, New York;(4) Joslin Diabetes Center and Harvard Medical School Boston, 02215, Massachusetts |
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| Abstract: | Thyrotropin (TSH) is composed of two subunits:  and  . Previously, we have mapped the TSH gene to human chromosome 6 and mouse chromosome 4. In this study we have located the human TSH gene on chromosome 1 and the mouse TSH gene to chromosome 3. These data suggest that the TSH gene lies in a conserved linkage group with the genes for amylase 1 and 2, nerve growth factor, and the protooncogene Nras. |
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