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血压负荷与诊室血压的关系
引用本文:贾友宏,王水强,鲍景隆,李一石,陶萍. 血压负荷与诊室血压的关系[J]. 中国分子心脏病学杂志, 2010, 10(6)
作者姓名:贾友宏  王水强  鲍景隆  李一石  陶萍
作者单位:1. 中国医学科学院北京协和医学院阜外心血管病医院心血管病研究所卫生部心血管药物临床研究重点实验室临床药理中心,北京市,100037
2. 北京中关村医院,北京市,100080
基金项目:"重大新药创制"科技重大专项
摘    要:目的探讨诊室血压与动态血压负荷关系。方法选取不同血压水平受试者90mmHg组,≥90mmHg组(≥95mmHg(轻、中度高血压))组,比较其诊室血压水平与对应的动态血压负荷值(血压负荷界值定义白天140/90mmHg、夜间120/80mmHg)及其相关性。结果入选53例成年(18岁)正常血压及轻、中度高血压患者,其中男37例,女16例,平均年龄53.7±8.7岁。坐位舒张压(DBP)90mmHg者(组1)31例,≥90mmHg者(组2)22例,其中≥95mmHg者16例。血压负荷:舒张压:组1的血压负荷为17%-29%(组间P0.01)。组2的为75%-84%。组3的为86%-91%。组2与组3比较P0.05。②收缩压:组1的血压负荷为33%-53%(组间P0.01)。组2的为75%-88%。组3的为76%-90%,与≥90mmHg比P0.05。诊室血压与其血压负荷的相关性(CC:相关系数):.舒张压:组1的CC为0.70-0.76,组2的为0.50-0.70。组3的为0.08-0.57。②收缩压:组1的为0.78-0.86,组2的为0.54-0.68,组3的为0.35-0.57。结论血压水平与血压负荷成正相关;轻中度血压与血压负荷相关性对临床更有指导意义。

关 键 词:诊室血压  动态血压  血压负荷

The Relationship between Ambulatory Blood Pressure Load and Office Blood Pressure Level
JIA You-hong,WANG Shui-qiang,BAO Jing-long,LI Yi-shi,TAO Ping. The Relationship between Ambulatory Blood Pressure Load and Office Blood Pressure Level[J]. Molecular Cardiology of China, 2010, 10(6)
Authors:JIA You-hong  WANG Shui-qiang  BAO Jing-long  LI Yi-shi  TAO Ping
Affiliation:1.1 Key Laboratory of Clinical Trials Research in Cardiovascular Drugs; Ministry of Health; Cardiovascular Institute and Fu Wai Hospital; Chinese Academy of Medical Sciences; Beijing 100037; China; 2Center for Drug Evaluation; State Food and Drug Administration; China(SFDA); 3ZhongGuanChun Hosiptal; Beijing 100080;
Abstract:Objective To investigate the relationship between ambulatory blood pressure(BP)load and office BP level.Methods To compare office BP levels with the corresponding value of BP load(The definition of BP load boundary value:the daytime>140/90mmHg,night>120/80mmHg)and their relationship.Results A total of 53 cases(> 18 years)with normal BP and mild to moderate hypertensive patients were recruited,including 37 males and 16 females,mean age 53.7± 8.7 years 31 cases with Sitting DBP< 90mmHg(group1),22 ...
Keywords:Office blood pressure  Ambulatory blood pressure  Blood Pressure Load
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