中文版量化的婴幼儿孤独症筛查量表信效度研究

目的 评估中文版量化的婴幼儿孤独症筛查量表(Q-CHAT)的信度和效度,以期为孤独症谱系障碍(ASD)的早期筛查提供合适的工具.方法 2019年7月—2020年1月分别采用量化的婴幼儿孤独症筛查量表(Q-CHAT)和儿童孤独症评定量表(CARS)对符合《精神障碍诊断和统计手册》第5版(DSM-5)ASD诊断标准的91例...

Reliability and validity of the Chinese version of the Quantitative Checklist for Autism in Toddlers

Objective To assess the reliability and validity of the Chinese version of the Quantitative Checklist for autism in toddlers (Q-CHAT), so as to provide an appropriate tool for early screening of autism spectrum disorder(ASD). Methods From July 2019 to January 2020, a total of 91 18- to 48-month-old ASD children diagnosed by DSM-5, alongside 45 age-matched individuals with other developmental disabilities (DD) and 60 typically developed (TD) children were screened by the Q-CHAT and Childhood Autism Rating Scale (CARS). Results The test-retest reliability was satisfactory (r=0.89).In addition, the Cronbach's α coefficient for internal reliability was 0.67(P<0.05).The Q-CHAT score was significantly correlated with the total CARS score (r=0.44, P<0.001).And correlation coefficients of 0.22—0.60 were obtained between the Q-CHAT score and total CARS score for various items.ROC analysis of ASD versus unaffected control subjects showed an area under the curve of 0.87, yielding maximum sensitivity (0.71) and specificity (0.92) with a cutoff of 45 points.Q-CHAT scores were significantly higher in ASD children compared with control children(t=9.42, P＜0.01), revealing sufficient discriminant validity. Conclusion Chinese version of Q-CHAT can be used for early screening of ASD children in urban Mandarin Chinese speaking populations with acceptable reliability and validity.