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多种评分系统在肝硬化合并食管胃底静脉曲张出血预后评估中的价值
作者姓名:向培正  李孟丽  傅燕
作者单位:1.昆明医科大学第二附属医院消化内科,云南 昆明 650101
基金项目:昆明医科大学第二附属医院院内科技计划项目(2018yk);昆明医科大学研究生创新基金资助项目(2020S187)
摘    要:目的 比较AIMS65、GBS、MGBS、EGBS、CRS、CANUKA、Child-Tureotte-Pugh(CTP)、MELD、MELD-Na评分系统在肝硬化合并食管胃底静脉曲张破裂出血患者(esophagealgastricvariceal bleeding,EGVB)预后评估中的价值,探讨影响肝硬化合并EGV...

关 键 词:肝硬化  食管胃底静脉曲张出血  评分系统
收稿时间:2022-01-19

Value of Multiple Scoring Systems in Evaluating the Prognosis of Liver Cirrhosis Complicated with Esophageal and Gastric Varices Bleeding
Institution:1.Dept. of Gastroenterology,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 6501012.Dept. of Respiratory Medicine,Affiliated Hospital of Yunnan University, Kunming Yunnan 650021,China
Abstract:  Objective  To compare the values of AIMS65, GBS, MGBS, EGBS, CRS, CANUKA, Child-Turcotte-Pugh (CTP), MELD, and MELD-Na scoring systems in the evaluation of the prognosis of patients with liver cirrhosis and EGVB, and explore the factors affecting the poor prognosis of patients with liver cirrhosis and EGVB.   Methods  A total of 169 patients diagnosed with liver cirrhosis and EGVB were divided into a good prognosis group and a poor prognosis group according to whether the patients had rebleeding or death in the hospital. The scores of each model at the time of admission of each patient were calculated, and the clinical characteristics of the two groups of patients were compared.   Results  There were 35 cases in the poor prognosis group and 134 cases in the good prognosis group. The scores of the poor prognosis group were higher than those of the good prognosis group. The AIMS65 score was the best in predicting whether the patient had a poor prognosis, and the difference was statistically significant (P < 0.05). The HB and ALB in the good prognosis group were higher than those in the poor prognosis group, and the PT and INR were lower than those in the poor prognosis group. The difference was statistically significant (P < 0.05). Multivariate logistic regression analysis suggested that ALB may be an independent protection factor for poor prognosis in patients with liver cirrhosis and EDVB.   Conclusion  AIMS65 is the best scoring system for prognostic evaluation of patients with liver cirrhosis and esophageal varices bleeding; ALB may be an independent protective factor for the poor prognosis of patients with liver cirrhosis and esophageal and gastric varices bleeding.
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