面部皮肤混合瘤的临床特征：18例报告并文献复习

 目的 探讨面部皮肤混合瘤的临床病理学特点、诊断与鉴别诊断。方法 对我院2017年3月至2021年9月间18例皮肤混合瘤患者资料进行回顾性分析。结果 18例患者中男9例，女9例；发病年龄为24~64岁。18例均发生于面部，鼻部最多见，均表现为单发无自觉症状的淡红色或肤色结节。初诊诊断为肿物待查12例，表皮囊肿2例，痣、皮脂腺瘤、钙化上皮瘤及瘢痕各1例。皮损组织病理均确诊为皮肤混合瘤，其中3例向小汗腺分化，15例向大汗腺分化。均行手术切除，随访2个月~1年，均无复发。结论 皮肤混合瘤是一种少见的皮肤良性肿瘤，确诊主要依赖组织病理学检查。

Clinical features of facial mixed skin tumor: a report of 18 cases and literature review

Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of mixed skin tumor. Methods We retrospectively analyzed the data of 18 patients with mixed skin tumors from our department from March 2017 to September 2021. Results The male to female ratio of the 18 cases was 1 ∶1, with the onset age of 24 to 64 years. All patients had facial involvement (most common on the nose), and exhibited asymptomatic singular nodule in light red or skin color. The histological findings revealed mixed skin tumor, including differentiation toward eccrine glands in 3 cases and apocrine glands in 15 cases. None of the 18 patients was clinically diagnosed as mixed skin tumor. All 18 patients underwent surgical resection and were followed up for 2 months to 1 year without recurrence. Conclusions Mixed skin tumor is a rare benign tumor. The diagnosis of the disease is mainly dependent on histopathological examination.