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孤独症谱系障碍儿童严重挑食与核心症状的关联
引用本文:艾女湉,张倩,杨亭,陈洁,陈立,代英,贾飞勇,武丽杰,郝燕,李玲,张婕,柯晓燕,衣明纪,洪琦,陈津津,方拴锋,王益超,王琦,金春华,李廷玉. 孤独症谱系障碍儿童严重挑食与核心症状的关联[J]. 中国儿童保健杂志, 2022, 30(4): 355-360. DOI: 10.11852/zgetbjzz2021-0398
作者姓名:艾女湉  张倩  杨亭  陈洁  陈立  代英  贾飞勇  武丽杰  郝燕  李玲  张婕  柯晓燕  衣明纪  洪琦  陈津津  方拴锋  王益超  王琦  金春华  李廷玉
作者单位:1.重庆医科大学附属儿童医院,儿童营养与健康重庆市重点实验室,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医学研究中心,儿童发育重大疾病国家国际科技合作基地,重庆 400000;2.吉林大学第一医院;3.哈尔滨医科大学儿童发育行为研究中心;4.华中科技大学同济医学院附属同济医院;5.海南省妇女儿童医学中心; 6.西安市儿童医院;7.南京医科大学附属脑科医院;8.青岛大学附属医院;9.深圳市宝安区妇幼保健院; 10.上海市儿童医院;11.河南省儿童医院;12.湖南省妇幼保健院;13.德阳市妇幼保健院;14.首都儿科研究所附属儿童医院
基金项目:国家自然科学基金面上项目(81771223);科技基础资源调查专项(2017FY101100,子课题编号2017FY101103)
摘    要:目的 分析孤独症谱系障碍(ASD)儿童严重挑食与其核心症状之间的关联,为ASD儿童的早期识别和精准干预提供参考.方法 纳入2018年5月~2019年12月在全国13城市的13家医院招募的2~7岁1 349名ASD儿童,1 170名典型发育(TD)儿童;采用自制问卷调查挑食情况,采用孤独症行为量表(ABC)、社会反应量表...

关 键 词:孤独症谱系障碍  严重挑食  核心症状  儿童

Association between picky eating and core symptoms in children with autism spectrum disorder
AI Nü-tian,ZHANG Qian,YANG Ting,CHEN Jie,CHEN Li,DAI Ying,JIA Fei-yong,WU Li-jie,HAO Yan,LI Ling,ZHANG Jie,KE Xiao-yan,YI Ming-ji,HONG Qi,CHEN Jin-jin,FANG Shuan-feng,WANG Yi-chao,WANG Qi,JIN Chun-hua,LI Ting-yu. Association between picky eating and core symptoms in children with autism spectrum disorder[J]. Chinese Journal of Child Health Care, 2022, 30(4): 355-360. DOI: 10.11852/zgetbjzz2021-0398
Authors:AI Nü-tian  ZHANG Qian  YANG Ting  CHEN Jie  CHEN Li  DAI Ying  JIA Fei-yong  WU Li-jie  HAO Yan  LI Ling  ZHANG Jie  KE Xiao-yan  YI Ming-ji  HONG Qi  CHEN Jin-jin  FANG Shuan-feng  WANG Yi-chao  WANG Qi  JIN Chun-hua  LI Ting-yu
Affiliation:Children's Hospital of Chongqing Medical University,Chongqing Key Laboratory of Child Health and Nutrition, Ministry of Education Key Laboratory of Child Development and Disorders,National Clinical Research Center for Child Health and Disorders,National International Science and Technology Cooperation Base for Critical Children's Development,Chongqing 400000,China
Abstract:Objective To investigate the relationship between severely picky eating and the core symptoms among children with autism spectrum disorder(ASD),so as to provide reference for early identification and targeted intervention. Methods From May 2018 to December 2019,1 349 children aged 2 to 7 years were enrolled in this study from 13 hospitals in 13 cities across the country,meanwhile 1 170 typically developed children were recruited. A self-made questionnaire was used to investigate the picky eating status of ASD children. Autism Behavior Scale(ABC),Social Response Scale(SRS) and Childhood Autism Rating Scale(CARS) were used to assess the core symptoms of ASD children. Linear regression was used to analyze the impact of severely picky eating on physical growth and core symptoms of ASD. Results The rate of severely picky eating in ASD children was 56.5%(763/1 349),which was 29.7%(348/1 170) in TD children. It was found that ASD and the age of children in two groups were risk factors for occurrence of severe picky eating after adjusting for confounding factors(OR=3.075,1.183,1.156,P<0.05). Severely picky eating significantly affected ASD children's weight,body mass index(BMI),scores of ABC scale and subscales,scores of SRAS scale and subscales(β=-0.220,-0.319,6.305,1.139,2.111,1.043,1.427,0.946,5.908,0.597,1.029,1.517,1.328,1.503,P<0.05). Conclusions There is a high incidence and persistence of severely picky eaters in autistic children. Severely picky eating has significant impact on children's weight growth and BMI,and is associated with core symptoms of ASD. Therefore,clinical medical staff should pay more attention to the assessment of picky eating behaviors in ASD children,so as to carry out early identification and precise intervention of children.
Keywords:autism spectrum disorder  severely picky eating  core symptoms  children  
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