云南省部分地区婚检人群生殖道沙眼衣原体感染情况及相关因素

  目的  了解云南省部分地区婚检人群生殖道沙眼衣原体（chlamydia trachomatis，CT）感染情况，为制定防控措施以及效果评估提供依据。  方法  采用横断面调查，选取云南省保山市、德宏州、红河州、临沧市、普洱市和西双版纳州婚检人群进行问卷调查，并采集尿液/宫颈分泌物样本进行CT核酸检测。   结果  共纳入研究对象1671例，总的人群感染率为6.64%（111/1671，95%CI:5.40%～7.80%）。其中男性感染率4.99%（42/841，95%CI:3.50%～6.50%），女性感染率8.31%（69/830，95%CI:6.40%～10.20%）。不同州市CT阳性率差异有统计学意义（P = 0.043），其中普洱市、德宏州和临沧市的感染率较高，为8.87%（29/327），8.64%（26/301）和7.94%（25/315）。年龄18～20岁（AOR = 4.346，95%CI:1.468～12.707）和文化程度为初中及以下的（AOR = 1.854，95%CI:1.071～3.211）更可能感染CT。  结论  云南省部分地区婚检人群中CT感染率具有地区、年龄和文化程度的差异。应加强性病防治知识的健康教育，进一步加强性病的检测能力，加大筛查力度和动员检测，尽可能地发现传染源，并进行规范化的治疗，以有效地控制生殖道沙眼衣原体的传播与流行。

Analysis of Genital Chlamydia Trachomatis Infection and Related Factors among Premarital Examination Population in Some Areas of Yunnan Province

  Objectives  To investigate the infection status of reproductive tract chlamydia trachomatis （CT） in premarital examination population in Yunnan Province, and to provide basis for prevention and control measures and effect evaluation.   Methods  A cross-sectional survey was conducted among the premarital examination population in Baoshan City, Dehong Prefecture, Honghe Prefecture, Lincang City, Pu’er City and Xishuangbanna Prefecture of Yunnan Province, and the urine/cervical secretion samples were collected for CT nucleic acid detection.   Results  A total of 1671 individuals were enrolled in this study. The overall CT prevalence in this population was 6.64% （111/1671, 95% CI: 5.40%～7.80%）, the prevalence among male and female were 4.99% （42/841, 95% CI: 3.50%～6.50%）, and 8.31% （69/830, 95% CI: 6.40%～10.20%）, respectively. The CT positive rates among the individuals attending premarital examination in different prefectures were statistically different （P = 0.043）, which were relatively higher in Pu’er City （8.87%, 29/327）, Dehong Prefecture （8.64%, 26/301） and Lincang City （7.94%, 25/315） . Aged ≤ 20 years （AOR = 4.346, 95%CI: 1.468～12.707） and education level of junior middle school and below （AOR = 1.854, 95%CI: 1.071～3.211） were more likely to be infected with CT.   Conclusion  The prevalence of CT among the premarital examination population showed statistical difference when stratified by region, age and education level. The health education on STD prevention knowledge and the testing ability of STD should be strengthened. The effective control of CT infection should be achieved by increasing the intensity of screening, finding the source of infection and carrying out standardized treatment.