肝硬化并发自发性细菌性腹膜炎临床研究进展*

目的 自发性细菌性腹膜炎(SBP)为目前肝硬化患者最常见的并发症之一,具有发病率高,疾病发展快,病死率高等特征。该病临床表现常不典型,腹腔感染的诊断主要基于腹腔积液白细胞计数。治疗则以经验性抗生素使用为主,联合调节肠道菌群、补充白蛋白等。有条件者可考虑肝移植。早期发现并积极实施干预对改善本病预后、降低病死率都有着重要的意义,但在有关SBP诊断、治疗和预防方面,仍面临巨大的挑战,需要深入研究进一步解决相关问题的策略,从而更好地指导临床实践,改善患者预后。

Spontaneous bacterial peritonitis in patients with liver cirrhosis

Objective The spontaneous bacterial peritonitis (SBP) is one of the most common complications in patients with cirrhosis, with high clinical incidence, rapid disease development and high mortality. The clinical manifestations of SBP are often not very typical, and the diagnosis of celiac infection is mainly based on the white blood cell counts in celiac fluid. The treatment is mainly empirical antibiotic administration and intestinal flora modulation. Early diagnosis and active intervention are of great importance to improve the prognosis and reduce the mortality, but there are still some great challenges in the diagnosis, treatment and prevention of the entity, which require in-depth study to further solve the relevant problems, so as to guide the clinical practice and improve the patient's prognosis.