基于加权TOPSIS法评价重组人血小板生成素的合理使用

目的:建立重组人血小板生成素(recombinant human thrombopoietin,Rh-TPO)合理性使用评价标准,为临床上提高Rh-TPO的合理性使用提供参考依据.方法:以Rh-TPO的说明书为基础,参照相关专家共识及循证医学证据制定合理性评价标准,采用加权TOPSIS法对甘肃省人民医院2020年出院病...

Evaluation of recombinant human thrombopoietin utilization based on weighted TOPSIS method

OBJECTIVE The evaluation criteria for the rational use of recombinant human thrombopoietin(Rh-TPO) is established, in order to provide a reference for improving the rational use of Rh-TPO in clinical practice.METHODS Based on the Rh-TPO instructions, the rationality evaluation criteria were formulated with reference to the consensus of relevant experts and evidence-based medical evidence, and the weighted TOPSIS method was used to evaluate the rationality of the discharge medical records of Gansu Provincial People's Hospital in 2020.RESULTS Among the 186 medical records using Rh-TPO, the ratio of patients with reasonable medication was 13.44%(25/186), the ratio of patients with basically reasonable medication was 81.19%(151/186), and the ratio of patients with irrational medication was 5.38%(10/186).CONCLUSION The weighted TOPSIS method can be used to evaluate the rationality of Rh-TPO.The results showed that the clinical application of Rh-TPO in this hospital was basically reasonable, but there were still some unreasonable uses of Rh-TPO, for example, the existence of inappropriate dosage, short course of treatment, and inappropriate timing of administration.It is necessary to strengthen management to ensure safe use of Rh-TPO in clinic.