| CO2点阵激光联合5-氨基酮戊酸光动力疗法治疗面部光线性角化病的疗效观察 |
| |
| 引用本文： | 王明,田歆,陆原,王霞,钟萍,柴宝,王鹏,黄春艳,黄长征.CO2点阵激光联合5-氨基酮戊酸光动力疗法治疗面部光线性角化病的疗效观察[J].皮肤性病诊疗学杂志,2022,29(4):342-346. |
| |
| 作者姓名： | 王明 田歆 陆原 王霞 钟萍 柴宝 王鹏 黄春艳 黄长征 |
| |
| 作者单位： | 1. 华中科技大学协和深圳医院皮肤科，广东深圳518052；2.广州市皮肤病防治所，广东广州510095；3.华中科技大学同济医学院附属协和医院皮肤科，湖北武汉430022 |
| |
| 基金项目： | 深圳市南山区科技计划项目（一般）（2020037） |
| |
| 摘 要： | 目的 观察CO2点阵激光联合5-氨基酮戊酸光动力疗法（ALA-PDT）治疗面部光线性角化病的临床疗效与安全性。方法 采用开放性、非对照性临床研究，对15例面部光线性角化病患者进行CO2点阵激光联合ALA-PDT治疗，共治疗1~5次，随访1年，观察疗效及安全性。 结果 2例患者经过1次治疗后获得完全缓解，4例2次治疗后完全缓解,9例3～5次治疗后完全缓解，随访12个月均无复发。 3例报告美容效果极好，7例报告美容效果良好，5例报告美容效果一般。治疗过程中，有11例患者轻微疼痛,4例明显疼痛。结论 CO2点阵激光联合ALA-PDT治疗面部光线性角化病有效，美容效果好。
|
| 关 键 词： | 光线性角化病 光动力疗法 5-氨基酮戊酸 CO2点阵激光 |
Efficacy of fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy on actinic keratosis in face |
| |
| WANG Ming,TIAN Xin,LU Yuan,WANG Xia,ZHONG Ping,CHAI Bao,WANG Peng,HUANG Chunyan,HUANG Changzheng.Efficacy of fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy on actinic keratosis in face[J].Diagnosis and Therapy Journal of Dermato-Venereology,2022,29(4):342-346. |
| |
| Authors: | WANG Ming TIAN Xin LU Yuan WANG Xia ZHONG Ping CHAI Bao WANG Peng HUANG Chunyan HUANG Changzheng |
| |
| Institution: | 1.Department of Dermatology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China； 2. Guangzhou Institute of Dermatology, Guangzhou 510095, China； 3.Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China |
| |
| Abstract: | Objective To observe clinical effects and safety of fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on facial actine keratosis (AK). Methods 15 cases of facial actine keratosis were given fractional CO2 laser combined with 5-ALA-PDT in the open and uncontrolled clinical study, for 1~5 times, followed up for 12 months. Results Two patients achieved complete remission after once treatment, 4 cases achieved complete remission after twice treatments, and 9 cases achieved complete remission after three to five times treatments. There was no recurrence after 12 months of follow up. 3 cases reported excellent cosmetic effect, 7 cases reported good cosmetic effect, and 5 cases reported average cosmetic effect. During the treatment,11 cases of the patients had slight pain,4 cases had obvious pain. Conclusion Fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy on facial actine keratosis is a safe, cosmetic and effective treatment. |
| |
| Keywords: | actine keratosisl photodynamic therapy 5-aminolevulinic acid fractional CO2 laser |
|
| 点击此处可从《皮肤性病诊疗学杂志》浏览原始摘要信息 |
| 点击此处可从《皮肤性病诊疗学杂志》下载免费的PDF全文 |
|
