儿童白癜风的特点及治疗进展

白癜风是常见的色素脱失性疾病，儿童白癜风在流行病学、临床表现、伴发疾病等方面有一定的特异性。另外，考虑儿童生长发育阶段的特殊性，儿童白癜风的治疗选择也不同于成人。尽管目前儿童白癜风的治疗仍以传统疗法为主，应用糖皮质激素、维生素D衍生物、钙调磷酸酶抑制剂等方法治疗白癜风在疗效方面仍具有局限性。因此包括Janus激酶抑制剂、阿法诺肽、前列腺素类似物等在内的新兴疗法被尝试引入白癜风的治疗中，未来有望应用于儿童群体。因此，本文结合儿童白癜风的特点、国内外指南及临床试验，对儿童白癜风的一般治疗及新兴治疗相关进展进行综述。

Characteristics of childhood vitiligo and the progress of its treatment

Vitiligo is a common depigmentation disease. Childhood vitiligo exhibits some characteristics in epidemiology, clinical manifestations, comorbidities, etc. In addition, considering the unique features of children′s growth and development stages, the therapeutic approaches for pediatric vitiligo are different from those for adults. Although traditional therapy is still the main treatment for childhood vitiligo, glucocorticoids, calcipotriol and other conventional methods have limited efficacy. Hence, new therapies, including Janus kinase inhibitor, afamelanotide and prostaglandin analogues, are introduced in the treatment of vitiligo and are expected to be applied to children. Therefore, this article summarizes the characteristics, domestic and foreign guidelines, clinical trials and the latest research progress in the treatment of childhood vitiligo.