鼻腔鼻窦癌综合治疗研究进展

鼻腔鼻窦癌病理类型多样,发病隐匿,临床症状无特异性,诊断时多为局部中晚期。目前治疗以手术联合放疗伴或不伴化疗的综合治疗模式为主,但术后患者器官功能保留率低、生活质量差,预后欠佳。近年来,随着手术及放化疗水平的提高,诊疗取得了一定进展,但具体方案仍存争议。本文对鼻腔鼻窦癌的主要研究进展及争议做一综述。

Recent advances in multidisciplinary therapy for sinonasal cancers

Sinonasal cancers (SNCs) are rare and heterogeneous diseases. Most patients present with locally advanced stage due to the insidious symptoms. In the majority of cases, the treatment strategy relies on the combination of surgery and radiotherapy, supplemented with or without chemotherapy. However, postoperative organ preserving rate is low, quality of life and clinical prognosis are poor. With recent advancement of surgical techniques, radiotherapy and chemotherapy techniques, certain progress has been reached in the diagnosis and treatment of SNCs. Nevertheless, the specific treatment regimen remains controversial. In this article, advances and controversies in SNC were reviewed.