经蝶入路显微外科治疗老年人垂体腺瘤

目的探讨老年人垂体腺瘤（ＳＰＡ）的手术疗效。方法总结经ＣＴ扫描或ＭＲＩ确诊的５６例ＳＰＡ经蝶显微外科治疗的临床资料，３５例经唇下－鼻中隔－蝶窦入路、２１例经鼻前庭－鼻中隔－蝶窦入路行肿瘤切除术。结果本组微腺瘤７例，大腺瘤３０例，巨大腺瘤１９例，术后无死亡。４８例获长期随访（平均３．５年），４１例恢复良好；７例术后平均３．４年肿瘤复发，其中２例再次手术，５例采用药物、放疗或放射外科治疗，于３个月时复查见患者恢复较为满意。结论采取经蝶显微外科治疗ＳＰＡ，是一种安全、有较的方法

Transsphenoidal microsurgical treatment of senile pituitary adenomas

Objective To probe the surgical curative effect on pituitary adenomas in senile patients. Methods The clinical data of 56 cases of pituitary adenomas and diagnosed by CT or MRI scan undergone transsphenoidal microsurgical therapy were analysed. Operations were performed via either sublabio septo sphenoidal approach or naso vestibulo sphenoidal approach. Results There were 7 cases of microadenomas, 30 macroadenomas and 19 giant adenomas. No death after operation. Long term follow up for average 3 5 years in 48 patients revealed good recovery in 41 patients (85 4%), contrasted with a 14 6% late recurrence rate in 7 cases with macroadenoma after operation for average 3 4 years. Two of the 7 patients with recurrence were again operated. Five of these received drug therapy, radiotherapy, and radiosurgery either alone or combined showed satisfactory recovery in 3 months. Conclusions The microsurgical technique via transsphenoidal approach to remove pituitary adenoma is a safe and effective method in senile patients.