CT引导经皮微波凝固治疗肝癌并发症的临床分析

目的分析CT引导经皮微波凝固治疗（PMCT）肝癌的相关并发症发生的原因、治疗及其预防方法。方法对68例肝癌患者接受CT引导PMCT治疗后的并发症的临床资料进行回顾性分析。结果肿瘤直径为2.013.8 cm,平均6.2 cm,其中64例接受PMCT前接受肝动脉化疗栓塞（TACE）。68例患者共接受120例次PMCT治疗,术中主要不良反应是迷走神经亢进反应。发生手术相关并发症7例次,包括肝脓肿和针道种植各2例次,气胸、心血管意外和巨大胆汁瘤合并感染各1例次;6例次并发症治愈,1例次种植肿瘤进展。结论CT引导PMCT治疗肝癌的并发症少且可以防治,并发症与穿刺路径、次数、凝固范围以及围手术期处理等有关。

Clinical analysis of operation-related complications of CT-guided percutaneous microwave coagulation therapy of liver malignancies

Objective To analyze the causes,treatment and prevention of operation-related complications in liver malignancy patients after CT-guided percutaneous microwave coagulation therapy (PMCT).Methods A total of 68 patients with liver malignancy underwent CT-guided PMCT and their complications were analyzed retrospectively.Results The tumor diameter was 2.0-13.8 cm,mean 6.2 cm.Transcatheter arterial chemoembolization (TACE) was performed before PMCT in 64 patients,and 68 patients received 120 times of PMCT (1-8 times per patient).The main untoward reaction of PMCT was vagus nerve accentuation.Seven patients (7/120,5.83%) had complications including needle-tract implantation (n=2),liver abscess (n=2),pneumatothorax (n=1),cardiovascular accident (n=l) and enormous biloma with infection (n=l),6 were treated finally,and implanted tumor advanced in 1 patient.Conclusion CT-guided PMCT in liver malignancies is a safe therapeutic option with low rate of operation-related complications,which can be prevented and treated.Complications of PMCT are associated with the needle tract,frequency,coagulation range and perioperative management.