Calidad de vida y síntomas persistentes tras hospitalización por COVID-19. Estudio observacional prospectivo comparando pacientes con o sin ingreso en UCI |
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Institution: | 1. Servicio de Anestesiología y Reanimación, Hospital Clínico Universitario de Santiago de Compostela. Instituto de investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, España;2. Servicio de Neumología, Hospital Clínico Universitario de Santiago de Compostela, Instituto de investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, España;3. Servicio de Medicina Interna, Hospital Clínico Universitario de Santiago de Compostela, Instituto de investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, España;4. Servicio de Anestesiología y Reanimación, Hospital Clínico Universitario de Ferrol, Ferrol, La Coruña, España;5. Unidad de Medicina Preventiva y Salud Pública, Departamento de Ciencias de la Salud, Universidade de A Coruña-INIBIC, La Coruña, España |
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Abstract: | BackgroundHospitalized COVID-19 patients are prone to develop persistent symptoms and to show reduced quality of life following hospital admission.MethodsProspective cohort study of COVID-19 patients admitted to a hospital from March 1 to April 30, 2020. The primary outcome was to compare health related quality of life and persistent symptoms six months after hospital admission, of COVID-19 patients who required ICU admission with those who did not.ResultsAmong the 242 patients hospitalized during the defined period of time, 44 (18.2%) needed ICU admission. Forty (16.5%) patients died during hospital admission. Two hundred and two (83.5%) patients were discharged alive from the hospital. At six months, 183 (75.6%) patients completed the questionnaires (32 ICU patients and 151 non ICU patients). Ninety-six (52.4%) reported decreased quality of life and 143 (78.1%) described persistent symptoms. More ICU patients showed worsening of their quality of life (71.9 vs. 43.7%, P = 0.004). There were no differences in the proportion of patients with persistent symptoms between ICU and non ICU patients (87.5 vs. 76.2%, P = 0.159). ICU patients showed more frequently dyspnea on exertion (78.1 vs. 47.7%, P = 0.02), dyspnea on light exertion (37.5 vs. 4.6%, P < 0.001), and asthenia (56.3 vs. 29.1, P = 0.003).ConclusionsSurvivors of COVID-19 needing hospitalization had persistent symptoms and a decline in the quality of life. ICU patients referred a large decrease of their quality of life compared with non ICU patients. |
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Keywords: | COVID-19 SARS-CoV-2 Critically ill patients Acute respiratory distress (ARDS) Health-related quality of life Functional status |
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