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Vascular Complications After Simultaneous Pancreas and Kidney Transplantation: A Case Report
Affiliation:1. Department of General Surgery and Transplantology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland;2. Centre of Postgraduate Medical Education, Warsaw, Poland;1. Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland;2. Military Institute of Medicine, Warsaw, Poland;3. Department of Surgical and Transplantation Nursing and Extracorporeal Therapies, Medical University of Warsaw, Warsaw, Poland;4. Department of Clinical Immunology; Medical University of Warsaw, Poland;1. Department of Transplantation Medicine, Nephrology and Internal Medicine, Medical University of Warsaw, Poland;2. Department of General and Transplantation Surgery, Medical University of Warsaw, Poland;1. Department of Biochemistry and Microbiology, Warsaw University of Life Sciences, Warsaw, Poland;2. Transplant Coordinating Center Poltransplant, Warsaw, Poland;3. Department of Emergency Medicine, Medical University of Warsaw, Warsaw, Poland;4. Department of Transplantology and Central Tissue Bank, Medical University of Warsaw, Warsaw, Poland
Abstract:A 51-year-old patient with type I diabetes and end-stage renal disease was qualified for a simultaneous kidney and pancreas transplant. The procedure was performed in a typical manner: arterial anastomosis to the right common iliac artery, the graft's portal vein with inferior vena cava, and side-to-side duodenal intestinal anastomosis. The kidney was implanted retroperitoneally.Six months after the transplant, the patient reported pain in the right lower abdomen, and imaging examinations revealed arterial anastomosis. Reconstruction of the right common iliac artery was performed with a Gore-Tex prosthesis and the pancreatic artery reanastomosed to the right external iliac artery. After the surgery, the function of the transplanted pancreas deteriorated, the level of C-peptide was decreased, and the patient required low doses of insulin. After another 8 months, the imaging studies revealed an aneurysm located in the bifurcation of the aorta up to the anastomosis of the pancreatic graft artery with the iliac artery. The patient was qualified for the implantation of an endovascular of 2 prosthesis, which improved the graft's function. After another 2 months, the presence of an aneurysm at the endovascular prosthesis was found again. The patient was requalified for endovascular prosthesis implantation. Currently, there is no aneurysm but the function of the pancreas graft is impaired, though the kidney graft function is good.Patients after simultaneous kidney and pancreas transplant are a group of patients with an increased risk of vascular complications. Treatment should take place in a multidisciplinary center.
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