基于VOSviewer和CiteSpace知识图谱的水蛭可视化分析

目的 分析破血消癥代表药水蛭在中医药领域相关研究文献,了解该药的研究脉络、热点和发展趋势。方法 计算机检索中国知网（CNKI）、Web of Science,1963年1月1日至2022年8月5日收录的水蛭涉及中医药领域的中、英文文献。采用VOSviewer1.6.18绘制核心作者、机构合作网络及高频关键词排序,运用CiteSpace6.1.R3进行关键词共现、聚类及突现展示。结果 共纳入中文文献943篇,英文文献43篇。结果提示核心作者较少,合作网络显示团队内部合作较多,缺乏团队间合作。中、英文关键词共现及聚类分析显示水蛭在中医药领域的研究热点主要为名医经验、临床研究、数据挖掘等,关键词突现提示冠心病、作用机制、数据库可能是未来发展的方向。结论 近年来水蛭在中医药领域的相关研究热度不断上升,名医经验与临床研究、数据挖掘、制剂研发及对于各类疾病的作用研究为其主流研究热点。以冠心病为主的心血管病临床研究、水蛭的作用机制研究以及基因组数据库的构建可能是未来研究趋势。

Visual analysis of Hirudo based on VOSviewer and CiteSpace knowledge graph

Objective To analyze the relevant literature of Shuizhi (Hirudo, leech), which is on behalf of the medicinal for breaking blood stasis and resolving mass in the field of traditional Chinese medicine (TCM), to comprehend the research thread, hotspot and development trend of Hirudo. Methods The Chinese and English literature which was about Hirudo in the field of TCM were systematically searched in Chinese National Knowledge Infrastructure (CNKI) and Web of Science, since January 1,1963 to August 5, 2022. VOSviewer1.6.18 was used to draw the network of core authors and institutions, sort the key words in order from most to least frequent. CiteSpace 6.1.R3 was used for key words co-occurrence, clustering and emergence display. Results A total of 943 Chinese literature and 43 English literatures were included in this study. The results showed that there were small number of core authors, the collaboration network showed that there were more intra-team cooperation, but less inter-team cooperation. The co-occurrence and cluster analysis of Chinese and English key words showed that the main research hotspots of Hirudo in field of TCM were experience of famous doctors, clinical research, data mining, etc. The emergent of key words suggested that coronary heart disease, mechanism of action, database could be for future directions. Conclusion The research on Hirudo in field of TCM has been increasing in recent year, with the experience of famous doctors, clinical research, data mining, preparation development and the studies on the effects of various diseases, being the mainstream research hotspots. The clinical study of cardiovascular diseases which is focused on coronary heart disease, the mechanism of Hirudo and the construction of genome database may be the future research trends.