Oncological Screening of Kidney Tumors After Renal Transplantation |
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Affiliation: | 1. Medical Imaging Center, Semmelweis University, Budapest, Hungary;2. Faculty of Medicine, Semmelweis University, Budapest, Hungary;3. Károli Gáspár University of the Reformed Church, Faculty of Humanities and Social Sciences, Budapest, Hungary;4. Department of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary;1. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;2. Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan;1. Gottsegen National Cardiovascular Center, Pediatric Heart Center, Budapest, Hungary;2. Department of Pediatrics, University of Debrecen Clinical Center, Debrecen, Hungary;3. 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary |
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Abstract: | BackgroundAmong renal transplant recipients, renal cell carcinoma in the native kidneys represents the most common solid tumor. At the Department of Surgery, Transplantation and Gastroenterology of Semmelweis University annual control abdominal ultrasound examination is recommended for transplant patients. Our goal was to evaluate the effectiveness of the ultrasound screening program at our institute and to learn about the characteristics of shrunken kidney tumors.MethodsRetrospectively, we processed the results of abdominal and pelvic ultrasound examinations of 1687 kidney transplant patients, which were performed at our institute between January 1, 2012 and December 31, 2016.ResultsA total of 26 tumors were detected during the abovementioned period of time, of which 18 were renal cancers. Renal cancer was significantly (P = 0.029) more common in men. Seventeen renal cancers were classified as stage I and one as stage IV disease. The mean time of dialysis was 37.73 ± 24.37 months. The mean time between kidney transplantation and tumor recognition was 7.9 ± 6.29 years. The 5-year survival was 66%; however, it should be noted that only 1 patient lost his life due to his tumor disease. The mean time between the last 2 ultrasound examinations was 27.8 ± 23.89 months. Only 57% of tumors were detected by screening. No significant differences in tumor size, stage, and survival could be detected between screened and nonscreened renal cancer patients.ConclusionsUltrasound examination at least every 2 years is an effective tool for the early detection of renal cell carcinoma of the shrunken kidneys. |
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