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Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers
Authors:Ireneusz Grulkowski   Jonathan J. Liu   Benjamin Potsaid   Vijaysekhar Jayaraman   Chen D. Lu   James Jiang   Alex E. Cable   Jay S. Duker   James G. Fujimoto
Affiliation:1Department of Electric Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA;2Advanced Imaging Group, Thorlabs Inc., Newton, NJ, USA;3Praevium Research Inc., Santa Barbara, CA, USA;4New England Eye Center, Tufts University, Boston, MA, USA
Abstract:We demonstrate swept source OCT utilizing vertical-cavity surface emitting laser (VCSEL)technology for in vivo high speed retinal, anterior segment and full eye imaging.The MEMS tunable VCSEL enables long coherence length, adjustable spectral sweep range and adjustablehigh sweeping rate (50–580 kHz axial scan rate). These features enable integration ofmultiple ophthalmic applications into one instrument. The operating modes of the device include:ultrahigh speed, high resolution retinal imaging (up to 580 kHz); high speed, long depth rangeanterior segment imaging (100 kHz) and ultralong range full eye imaging (50 kHz). High speed imagingenables wide-field retinal scanning, while increased light penetration at 1060 nm enablesvisualization of choroidal vasculature. Comprehensive volumetric data sets of the anterior segmentfrom the cornea to posterior crystalline lens surface are also shown. The adjustable VCSEL sweeprange and rate make it possible to achieve an extremely long imaging depth range of ~50 mm, and todemonstrate the first in vivo 3D OCT imaging spanning the entire eye fornon-contact measurement of intraocular distances including axial eye length. Swept source OCT withVCSEL technology may be attractive for next generation integrated ophthalmic OCT instruments.OCIS codes: (110.4500) Optical coherence tomography, (120.4640) Optical instruments, (140.3600) Lasers, tunable, (170.4460) Ophthalmic optics and devices, (170.4470) Ophthalmology
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