右美托咪定联合舒芬太尼用于小儿大面积烧伤削痂植皮术后镇痛的效果

目的 分析对行削痂植皮术治疗大面积烧伤的患儿术后采用右美托咪定联合舒芬太尼的镇痛效 果。方法 选取东明县妇幼保健院2021年1月-2023年12月收治的74例小儿大面积烧伤削痂植皮术患者为 研究对象，采用随机数字表法分为对照组和观察组，各37例。对照组予以舒芬太尼术后镇痛，观察组予 以右美托咪定联合舒芬太尼术后镇痛，比较两组术后镇静、镇痛效果以及不良反应发生情况。结果 观 察组术后2、6、12、24、48 h Ramsay镇静评分高于对照组，差异有统计学意义（P ＜0.05）；观察组术后 2、6、12、24、48 h的FACES疼痛评分均低于对照组，差异有统计学意义（P ＜0.05）；观察组不良反应发 生率为5.41%，低于对照组的18.92%，差异有统计学意义（P ＜0.05）。结论 对行削痂植皮术治疗的大面 积烧伤的患儿术后采用右美托咪定+舒芬太尼能够有效提升镇静、镇痛效果，降低不良反应发生几率。

Effect of Dexmedetomidine Combined with Sufentanil on Postoperative Analgesia in Children with Extensive Burn After Eschar Shaving and Skin Grafting

Objective To analyze the analgesic effect of dexmedetomidine combined with sufentanil on children with extensive burn after eschar shaving and skin grafting. Methods From January 2021 to December 2023, 74 children with extensive burn who underwent eschar shaving and skin grafting in Dongming County Maternal and Child Health Care Hospital were selected as the research objects. They were divided into control group and observation group by random number table method, with 37 children in each group. The control group was given sufentanil for postoperative analgesia, and the observation group was given dexmedetomidine combined with sufentanil for postoperative pain. The postoperative sedation, analgesic effect and adverse reactions were compared between the two groups. Results The Ramsay sedation score of the observation group was higher than that of the control group at 2, 6, 12, 24 and 48 h after operation, and the difference was statistically significant (P <0.05). The FACES pain scores of the observation group at 2, 6, 12, 24 and 48 h after operation were lower than those of the control group, and the differences were statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 5.41%, which was lower than 18.92% in the control group, and the difference was statistically significant (P <0.05). Conclusion Dexmedetomidine+sufentanil can effectively improve the sedative and analgesic effects and reduce the incidence of adverse reactions in children with large area burns treated by eschar shaving and skin grafting.