Heterozygote advantage in cystic fibrosis: mosquito tests |
| |
Authors: | Maurice Super DirkJ. van Schalkwyk |
| |
Affiliation: | Institute for Biostatistics, MRC, Parrow, South Africa;Department of Paediatrics, State Hospital, Windhoek, South West Africa –Namibia |
| |
Abstract: | Tests to demonstrate a preference by mosquitoes for stinging controls as opposed to obligate heterozygotes for Cystic Fibrosis proved negative. If a heterozygote advantage caused a lower malarial incidence in carriers in South West Africa, it must have worked through the malarial parasite being adversely affected by a serum factor. This remains to be tested. |
| |
Keywords: | Cystic fibrosis heterozygote advantage malaria mosquito tests |
|
|