射频热凝术联合臭氧盘外注射治疗腰椎间盘突出症的疗效分析

目的观察射频热凝术联合臭氧盘外注射治疗腰椎间盘突出症的临床疗效。方法分析202 例腰椎间盘突出症患者，依据手术方式不同分为射频组、臭氧组、射频联合臭氧组（联合组）。通过视觉模拟（VAS）评分、 Macnab 疗效评价（观察指标包括有效率及优良率）和Oswestry 功能障碍指数（ODI）评分观察3 组患者术后1 d、术后 1 个月、6 个月、12 个月的临床疗效。结果3 组间性别构成比、年龄、病程年限、术前VAS 评分和ODI 评分差异均无统计学意义（P＞0.05）。全部患者手术顺利，均未发生间盘感染，无脊髓、神经、血管脏器损伤等并发症。联合组术后1 个月、6 个月、12 个月的VAS 评分和ODI 评分均低于射频组和臭氧组，而后两组不同时点差异无统计学意义（P＞0.05）。3 组术后1 个月、6 个月、12 个月有效率差异无统计学意义，但联合组以上时点的优良率高于射频组和臭氧组(P < 0.05)，后两组优良率差异无统计学意义。结论射频热凝术联合臭氧盘外注射治疗腰椎间盘突出症，两项技术互相取长补短，治疗效果好，不良反应少，是临床上值得推广的一项微创介入技术。

The efficacy analysis of radiofrequency therapy combined with ozone injection in the treatment of lumbar disc protrusion

Abstract：Objective To assess the efficacy of radiofrequency therapy combined with ozone injection in the treatment of lumbar disc protrusion. Methods A total of 202 patients with lumbar disk protrusion were included and divided into three groups: radiofrequency (RF) group, ozone (Oz) group, and combination (Co) group. The efficacy was evaluated by visual analogue scale (VAS), Macnab curative effect evaluation, and oswestry disability index (ODI) at 1d, 1m and 6m after treat⁃ ment. Results There were no significant differences in gender, age, the course of disease, preoperative VAS scores and ODI scores (P > 0.05). All patients were operated successfully. There were no infection of the intervertebral disc, no compli⁃ cations of spinal cord, nerve and no blood vessel injury. There were no significant differences in preoperative VAS and ODI scores between three groups. The VAS and ODI scores were significantly lower at 6 month and 12 month after operation in Co group combined with those of RF group and Oz group. There were no significant differences in these two scores between RF group and Oz group (P > 0.05). There were no significant differences in effective rates at 1d, 6 month and 12 month after operation between three groups (P > 0.05). But the excellent and good effective rates were higher in Co group than those of RF and Oz groups. There were no significant differences in excellent and good effective rates between RF group and Oz group. Conclusion The therapy of radiofrequency combined with ozone injection is an efficient and mini-invasive tech⁃ nique for the treatment of lumbar disc protrusion and worth promoting.