| 中脑导水管周围灰质内脑啡肽对催产素增强电针镇痛的影响 |
| |
| 引用本文： | 刘文彦,王宏,冯学泉,王曙光,张艳霞,白波. 中脑导水管周围灰质内脑啡肽对催产素增强电针镇痛的影响[J]. 济宁医学院学报, 2003, 26(1): 8-10 |
| |
| 作者姓名： | 刘文彦 王宏 冯学泉 王曙光 张艳霞 白波 |
| |
| 作者单位： | 1. 济宁医学院生理学教研室
2. 泰山医学院神经生物教研室 |
| |
| 基金项目： | 山东省自然科学基金资助课题 (No .Q98C0 112 4 ) |
| |
| 摘 要： | 目的：探讨中脑导水管周围灰质(PAG)内催产素(OT)与内源性脑啡肽在电针镇痛中的相互关系。方法：以钾离子透入法引起大鼠甩尾反应的电流强度(mA)为痛反应的指标，观察向PAG内注入OT和抗脑啡肽血清，对大鼠电针镇痛效应的影响。结果：PAG内注入抗脑啡肽血清后，能明显降低电针镇痛的效应；但预先注入抗脑啡肽血清，并不能阻断OT增强电针镇痛的作用。结论：PAG内OT在电针镇痛中的作用不依赖于PAG内的内源性脑啡肽。
|
| 关 键 词： | 中脑导水管周围灰质 催产素 内源性 脑啡肽 电针镇痛 大鼠 |
EFFECT OF MET- ENKEPHALIN ON THE ENHANCEMENT OF ELECTROACUPUNCTURE ANALGESIA INDUCED BY OXYTOCIN IN PERIAQUEDUCTAI GRAY OF RATS |
| |
| Liu Wenyan,Wang Hong,Feng Xuequan,et al. EFFECT OF MET- ENKEPHALIN ON THE ENHANCEMENT OF ELECTROACUPUNCTURE ANALGESIA INDUCED BY OXYTOCIN IN PERIAQUEDUCTAI GRAY OF RATS[J]. Jounal of Jinning Medical College, 2003, 26(1): 8-10 |
| |
| Authors: | Liu Wenyan Wang Hong Feng Xuequan et al |
| |
| Abstract: | Objective To study the effect of oxytocin( OT ) on electroacupuncture analgesia in periaqueductal gray(PAG) and its rel ation to endogenous met-enkephalin. Methods The potassium iontophoresis induced tail-flick was us ed to measure the pain threshold. Results OT administration induced a enhancement of electroacup uncture analgesia.Furthermore,pre-injection of AMEKS in PAG not could weake n analgesia effect of OT. Conclusion These data suggest the enhancement of electroacupun cture analgesia by OT is not dependent upon the met-enkephalin in PAG. |
| |
| Keywords: | oxytocin anti-met-enkephalin serum periaqueducta l gray electroacupuncture analgesia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
