磁共振DWI信号及ADC值在肝脏疾病鉴别诊断中的应用价值

目的：探讨磁共振扩散加权像（DWI）信号和表观扩散系数（ADC）值在肝脏良、恶性疾病鉴别诊断中的应用价值。方法：回顾性分析2011-03～2013—05120例185个肝占住性病灶，其中肝囊肿77个病灶，肝血管瘤75个病灶，肝细胞癌33个病灶进行DWI扫描，并测量表现扩散系数值（ADC值）。结果；肝囊肿、肝血管瘤、原发性肝细胞癌ADC值分别为（2．63±0．11）×10^-3mm^2／s、（1．72±0．12）×10^-3mm^2／s、（1．03±0．08）×10^-3mm^2／s，ADC值逐渐减小。各组之间差异均存在统计学意义（P〈0．01）。结论：分析肝内病灶DWI信号及ADC值对肝脏良、恶性病变的鉴别诊断有重要价值，在常规肝脏检查应用扩散成像能够检测出平扫无法发现的小病变，但是定性诊断还是有一定的限制。

Magnetic resonance DWI signal and the ADC value in the differential diagnosis of liver disease

Objective： To investigate the diffusion weighted magnetic resonance imaging （DWI） and appar- ent diffusion coefficient （ADC） value of the signal value of differential diagnosis in benign and malignant liver diseases. Methods： We retrospectively analyzed 120 cases with 185 liver lesions from 2011 March --2013 May, including 77 lesions of hepatic cysts, 75 hepatic hemangioma lesions. We DWI scanned liver cancer in 33 lesions, and measured apparent diffusion coefficient （ADC value）. Results： The liver cyst, hemangioma of liver, hepatocellular carcinoma ADC values were（2.63±0. 11）×10^-3mm^2/s, （1.72±0. 12）× 10^-3mm^2/s, （1.03± 0. 08）×10^-3mmZ/s, and ADC values were decreased gradually. Differences between groups were statistically significant （P 〈 0. 01）. Conclusion： The analysis of the hepatic lesions DWI signal and the ADC value are im- portant for diagnosis and differential diagnosis of hepatic benign, malignant lesions. They can detect small lesions which cannot be found in conventional liver test application of diffusion weighted imaging, but they have certain restrictions in qualitative diagnosis.