TCD结合屏气试验评价Hhcy者脑血管反应性 |
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引用本文: | 张有余,张晓梅,白岩.TCD结合屏气试验评价Hhcy者脑血管反应性[J].佳木斯医学院学报,2014(1):32-33. |
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作者姓名: | 张有余 张晓梅 白岩 |
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作者单位: | 佳木斯大学附属第一医院,黑龙江佳木斯154003 |
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摘 要: | 目的:评价高同型半胱氨酸血症者脑血管反应性.方法:高同型半胱氨酸血症者42例(年龄23~65岁,男24例,女18例),正常人群50例(年龄20~68岁,男29例,女21例),两组间年龄差异及性别比例无统计学意义.嘱托受试者平静呼吸5~10min后屏气25s,分别记录屏气前后MCA平均血流速度Vm及搏动指数PI值.并计算其变化值及变化率.结果:高同型半胱氨酸血症组平均血流速度Vm较对照组增快(P<0.01),搏动指数PI高于对照组(P<0.05).高同型半胱氨酸血症者组平均血流速度Vm变率为低于对照组,差异有统计学意义(P<0.01).结论:①高同型半胱氨酸血症者脑血管反应性降低.②TCD检查可以为高同型半胱氨酸血症者早期防治提供理论依据.
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关 键 词: | 高同型半胱氨酸血症 脑血管反应性 经颅多普勒 屏气试验 |
The evaluation of cerebrovascular reactivity by TCD combined with breath holding test |
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Institution: | ZHANG You - yu, ZHANG Xiao - mei, BAI Yah (First Affiliated Hospital of Jiamusi University,Jiamusi 154003, China) |
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Abstract: | Objective. To evaluate hyperhomocysteinemia cerebral vascular reactivity. Methods. There were 42 cases in Hyper homocysteinemia group (age 23-65 years, 24 males, and 18 females), 50 cases of nor- mal people (age 20-68 years old, male 29, female 21). The differences of age and sex ratio in two groups have no statistically significance. We asked the subjects to hold breath 25s after breath 5-10 minutes. We recorded average flow velocity Vm of MCA and pt, lsatility index PI respectively before and after breath hold, then we calculated the change value and change rate. Results: The average blood flow velocity of Vm in Hyper homocysteinemia group increased faster than that in control group (P 〈 0.01). Pulsatility index and resistance index of RI are higher than those in control group (P 〈 0.05). Hyper homocysteinemia group average blood flow velocity of Vm was lower than that in the control group. The difference was statistically significant (P 〈 0.01). Conclusion: The reactivity of Hyper homocysteinemia cerebral vascular reduced. TCD examina- tion can provide theoretical basis for homocysteine early prevention. |
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Keywords: | high homocysteine cerebrovascular reactivity transcranial doppler breath holding test |
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