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治疗脂肪肝的药物临床应用评价
引用本文:宋健,张沐新,孙薇,杨晓虹,周小平.治疗脂肪肝的药物临床应用评价[J].中国药物化学杂志,2012(5):452-456.
作者姓名:宋健  张沐新  孙薇  杨晓虹  周小平
作者单位:吉林大学药学院药物化学教研室
基金项目:吉林省中医药管理局中医药科技项目(2010-pt045)
摘    要:脂肪肝是由多种原因引起的肝细胞内脂肪堆积过多而导致的病变。脂肪肝已成为仅次于病毒性肝炎的第二大肝病,并被认为是隐蔽性肝硬化的常见原因之一。脂肪肝可分为酒精性脂肪肝和非酒精性脂肪肝。目前,临床上并没有针对脂肪肝的特效药物,多采用药物对症治疗的方法。本文对近年来脂肪肝的治疗药物的临床应用进行总结。

关 键 词:酒精性脂肪肝  非酒精性脂肪肝  治疗药物

Clinical application of therapeutic drugs of fatty liver
SONG Jian,ZHANG Mu-xin,SUN Wei,YANG Xiao-hong,ZHOU Xiao-ping.Clinical application of therapeutic drugs of fatty liver[J].Chinese Journal of Medicinal Chemistry,2012(5):452-456.
Authors:SONG Jian  ZHANG Mu-xin  SUN Wei  YANG Xiao-hong  ZHOU Xiao-ping
Institution:(Department of Medicinal Chemistry,College of Pharmacy,Jilin University,Changchun 130021,China)
Abstract:Fatty liver is a lesion caused by excessive accumulation of fat in the liver cells which is caused by a variety of reasons.Fatty liver has become the second liver disease after viral hepatitis,and is recognized as a common cause of hidden cirrhosis.Fatty liver can be divided into alcoholic fatty liver and non-alcoholic fatty liver.Currently,no specific drugs can be used for the treatment of fatty liver besides using symptomatic drugs.In this review,many symptomatic drugs for fatty liver were listed.
Keywords:alcoholic fatty liver disease  non-alcoholic fatty liver disease  therapeutic drug
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