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盐酸氨溴索对小儿肺炎血清SAA和C-RP的影响
引用本文:姜林,方凤,郭品娥. 盐酸氨溴索对小儿肺炎血清SAA和C-RP的影响[J]. 儿科药学杂志, 2003, 9(5): 19-20
作者姓名:姜林  方凤  郭品娥
作者单位:1. 解放军第359医院,江苏,镇江,212001
2. 解放军第二军医大学附属长海医院,上海,200043
摘    要:目的:探讨盐酸氨溴索对肺炎患儿血清淀粉样蛋白A(SAA)和C鄄反应蛋白(C鄄RP)的影响。方法:将病人分为治疗组(31例)和对照组(30例),对照组常规抗感染治疗,治疗组在对照组基础上加用氨溴索氧气驱动雾化吸入治疗5d,记录每天用药前后各临床指标和SAA和C鄄RP浓度变化。结果:治疗组用药前后SAA和C鄄RP浓度比较差异有显著性(P<0.01);治疗组与对照组比较也有显著性差异(P<0.05)。结论:氨溴索能使血清SAA和C鄄RP明显下降,提高抗生素疗效,缩短疗程。

关 键 词:盐酸氨溴索 小儿 肺炎 血清 SAA C-RP 淀粉样蛋白A C-反应蛋白
文章编号:1672-108X(2003)05-0019-02
修稿时间:2003-04-28

The effect of ambroxol on serum amyloid A and C-reactive protein of children with pneumonia
JIANG Lin ,FANG Feng ,GUO Pin - e. The effect of ambroxol on serum amyloid A and C-reactive protein of children with pneumonia[J]. Journal of Pediatric Pharmacy, 2003, 9(5): 19-20
Authors:JIANG Lin   FANG Feng   GUO Pin - e
Affiliation:JIANG Lin 1,FANG Feng 2,GUO Pin - e 2
Abstract:Objective:To study the effect of ambroxol on serum amyloid A(SAA)and C-reactive protein(C-RP)of children with pneumonia.Methods:Patients were divided into treatment group(31cases)and control group(30cases).In treatment group,ambroxol was used under the condition of antibiotics.In control group ambroxol was not used.Clinical data and SAA,C-RP were evaluated before treatment and5days after treatment.Results:Before and after treatment,there are significant changes of SAA and C-RP(P<0.01).There are also significant differences between treatment group and control group(P<0.01).Conclusions:SAA and C-RP decreased obviously after using ambroxol.Ambroxol could increase the effect of antibiotics and shortened the treatment period.
Keywords:Ambroxol  Serum amyloid A  C-reactive protein  Pneumonia  
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