邢台市干部职工冠状动脉粥样硬化性心脏病患病率及危险因素研究

目的了解邢台市干部职工冠状动脉粥样硬化性心脏病(coronary atherosclerotic heart disease,CHD)患病率及其相关因素。方法自行设计流行病学调查表,对30 068名干部职工进行问卷调查、体格检查和生化检测。患病率的比较应用χ~2检验。相关因素应用logistic回归分析。结果邢台市干部职工CHD的患病率为4.59%(1 381/30 068)。单因素分析显示,年龄、性别、血脂异常、高血压、糖尿病、肥胖、吸烟、饮酒、运动量、高脂饮食、高糖饮食、髙盐饮食、嗜好饱食和家族史均与CHD的患病相关联(P<0.001)。多因素分析显示,CHD患病的危险因素为年龄大(OR=4.49,95%CI:3.30~6.58)、男性(OR=4.46,95%CI:3.13~6.45)、血脂异常(OR=41.96,95%CI:27.50~64.02)、高血压(OR=49.64,95%CI:33.87~88.24)、糖尿病(OR=58.20,95%CI:43.18~97.71)、肥胖(OR=23.58,95%CI:12.30~45.12)、吸烟(OR=17.19,95%CI:5.31~15.82)、饮酒(OR=4.30,95%CI:3.18~5.90)、运动量小(OR=3.34,95%CI:1.86~5.99)、高脂饮食(OR=23.01,95%CI:12.65~41.86)、高糖饮食(OR=21.11,95%CI:12.05~36.32)、髙盐饮食(OR=6.88,95%CI:3.83~12.16)、嗜好饱食(OR=12.01,95%CI:6.90~20.81)和家族史(OR=13.46,95%CI:4.16~12.12)。结论邢台市干部职工CHD的患病率较高,CHD的患病与年龄大、男性、血脂异常、高血压、糖尿病、肥胖、吸烟、饮酒、运动量小、高脂饮食、高糖饮食、髙盐饮食、嗜好饱食和家族史密切相关。

Prevalence rate and risk factors of coronary atherosclerotic heart disease among cadres and workers in Xingtai city

Objective To investigate the prevalence rate of coronary atherosclerotic heart disease (CHD) and its related factors among cadres and workers in Xingtai city. Methods A self-designed epidemiological questionnaire survey and physical and biochemical examinations were conducted among 30,068 cadres and workers. Chi-square test was used to compare the prevalence rate, and the related factors were analyzed by logistic regression. Resultss The prevalence rate of CHD among the cadres and workers in Xingtai city was 4.59% (1,381/30,068). Single factor analysis indicated that age, gender, dyslipidemia, hypertension, diabetes, obesity, smoking, drinking, amount of exercise, high fat diet, high sugar diet, high salt diet, indulgence in appetite and family history were all associated with the prevalence of CHD. Multiple-factor analysis indicated that the risk factors for the prevalence of CHD included advanced age (OR=4.49, 95%CI:3.30-6.58), males (OR=4.46, 95%CI:3.13-6.45), dyslipidemia (OR=41.96, 95%CI:27.50-64.02), hypertension (OR=49.64, 95%CI:33.87-88.24), diabetes (OR=58.20, 95%CI:43.18-97.71), obesity(OR=23.58, 95%CI:12.30-45.12), smoking (OR=17.19, 95%CI:5.31-15.82), drinking (OR=4.30, 95%CI:3.18-5.90), a small amount of exercise(OR=3.34, 95%CI:1.86-5.99), high fat diet(OR=23.01, 95%CI:12.65-41.86), high sugar diet (OR=21.11, 95%CI:12.05-36.32), high salt diet (OR=6.88, 95%CI:3.83-12.16), indulgence in appetite (OR=12.01, 95%CI:6.90-20.81) and family history (OR=13.46, 95%CI:4.16-12.12). Conclusions The prevalence rate of CHD among the cadres and workers in Xingtai city is high, and CHD prevalence is closely related to advanced age, males, dyslipidemia, hypertension, diabetes, obesity, smoking, alcohol consumption, a small amount of exercise, high fat diet, high sugar diet, high salt diet, satiety and family history.