A Single-Center Experience with Intracardiac Thrombosis in Children with Dilated Cardiomyopathy |
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Authors: | Soo-Han Choi Soo In Jeong Ji-Hyuk Yang I-Seok Kang Tae-Gook Jun Heung-Jae Lee June Huh |
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Institution: | (1) Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Korea;(2) Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Korea; |
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Abstract: | Intracardiac thrombosis in patients with a dilated cardiomyopathy can be life threatening. This study investigated the incidence,
risk factors, and outcome of intracardiac thrombosis in children with dilated cardiomyopathy. A retrospective review of the
clinical records was performed in 83 children with dilated cardiomyopathy diagnosed from January 1995 to December 2008. Intracardiac
thrombi were detected in 5 patients (6.0%). The intracardiac thrombi were found mainly in the left ventricle (n = 3). One patient had a thrombus in the left atrium at the time of diagnosis, and a right ventricular thrombus was found
in 1 patient with unrepaired ventricular septal defect complicated by pulmonary hypertension. Intracardiac thrombosis developed
during rapid deterioration of ventricular function, and all patients had a poor ejection fraction of the left ventricle. All
patients were treated with heparinization, and thrombectomy was performed in 1 patient. Three patients achieved complete resolution
of the thrombus without further embolic complications. Careful evaluation and aggressive anticoagulation are necessary for
the prevention of intracardiac thrombosis in children with poor ventricular function, especially during rapid deterioration
of ventricular function. |
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