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乳香属药用植物中乳香酸类化学成分、生物活性及其作用机制研究进展
引用本文:蔡红蝶,宿树兰,周卫,钱大玮,段金廒.乳香属药用植物中乳香酸类化学成分、生物活性及其作用机制研究进展[J].中草药,2016,47(12):2175-2181.
作者姓名:蔡红蝶  宿树兰  周卫  钱大玮  段金廒
作者单位:南京中医药大学 江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023;南京中医药大学 江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023;南京中医药大学 江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023;南京中医药大学 江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023;南京中医药大学 江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023
基金项目:国家自然科学基金资助项目(30973885,81373889);教育部新世纪优秀人才支持计划项目(NCET-13-0873)
摘    要:乳香为橄榄科植物乳香树或同属植物的胶状树脂,在我国具有悠久的药用历史。研究表明,药用乳香效应成分主要为乳香酸类成分,具有抗炎、抗菌、抗肿瘤等药理活性。在广泛的文献检索基础上,对乳香属药用植物中乳香酸类成分的种类、提取方法、生物活性、作用机制及其代谢转化研究进行较为系统地整理分析与归纳总结,为其进一步深入研究和开发利用提供科学依据。

关 键 词:乳香属  乳香  乳香酸类成分  抗炎  抗菌  抗肿瘤
收稿时间:2016/1/12 0:00:00

Research progress in boswellic acids from medicinal plants in Boswellia Roxb. ex Colebr. and their pharmacological action as well as mechanisms
CAI Hong-die,SU Shu-lan,ZHOU Wei,QIAN Da-wei and DUAN Jin-ao.Research progress in boswellic acids from medicinal plants in Boswellia Roxb. ex Colebr. and their pharmacological action as well as mechanisms[J].Chinese Traditional and Herbal Drugs,2016,47(12):2175-2181.
Authors:CAI Hong-die  SU Shu-lan  ZHOU Wei  QIAN Da-wei and DUAN Jin-ao
Institution:Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Abstract:Frankincense, the gum resin from the plants in Boswellia Roxb. ex Colebr. or the other plants belonging to Burseraceae, has a long history as a medicine in China. The investigations on the pharmacological effects of the resin have demonstrated its anti-inflammatory, antisepsis, antitumor effects, etc. This article classifies and summarizes the preparation methods, pharmacological effects, action mechanisms, and metabolic process in vivo or in vitro of boswellic acids compounds, and providing the reference for the further development and utilization of boswellic acids and medicinal plants in Boswellia Roxb. ex Colebr.
Keywords:Boswellia Roxb  ex Colebr    frankincense  boswellic acids  anti-inflammation activity  antibiosis activity  antitumor activity
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