| 马鞭草HPLC指纹图谱建立及指标性成分的测定 |
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| 引用本文： | 刘素香,白雪,刘毅,田子钰,丁连峰,葛德助,张铁军.马鞭草HPLC指纹图谱建立及指标性成分的测定[J].中草药,2016,47(12):2069-2073. |
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| 作者姓名： | 刘素香 白雪 刘毅 田子钰 丁连峰 葛德助 张铁军 |
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| 作者单位： | 天津药物研究院, 天津 300193;中药现代制剂与质量控制技术国家地方联合工程实验室(天津), 天津 300193;天津药物研究院, 天津 300193;天津药物研究院, 天津 300193;中药现代制剂与质量控制技术国家地方联合工程实验室(天津), 天津 300193;天津药物研究院, 天津 300193;哈尔滨商业大学, 黑龙江 哈尔滨 150076;安徽济人药业有限公司, 安徽 亳州 236800;安徽济人药业有限公司, 安徽 亳州 236800;天津药物研究院, 天津 300193;中药现代制剂与质量控制技术国家地方联合工程实验室(天津), 天津 300193 |
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| 摘 要： | 目的 建立马鞭草Verbena officinalis的HPLC指纹图谱,并测定其主要成分的量,为马鞭草的质量控制提供可靠方法。方法 采用HPLC法测定多批次马鞭草指纹图谱及主要成分量,并对各批次指纹图谱进行相似性和聚类分析的对比分析以及主要成分的量对比分析。结果 马鞭草药材各批次间主要成分量和指纹图谱均有差异。结论 所建立的指纹图谱及主要成分测定方法为马鞭草的质量评价提供了科学依据。
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| 关 键 词： | 马鞭草 HPLC 指纹图谱 疏风解毒胶囊 指标性成分 |
| 收稿时间： | 2016/3/24 0:00:00 |
Establishment of HPLC fingerprint of Verbenae officinalis and determination of multi-components |
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| LIU Su-xiang,BAI Xue,LIU Yi,TIAN Zi-yu,DING Lian-feng,GE De-zhu and ZHANG Tie-jun.Establishment of HPLC fingerprint of Verbenae officinalis and determination of multi-components[J].Chinese Traditional and Herbal Drugs,2016,47(12):2069-2073. |
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| Authors: | LIU Su-xiang BAI Xue LIU Yi TIAN Zi-yu DING Lian-feng GE De-zhu and ZHANG Tie-jun |
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| Institution: | Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China;Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China;Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;College of Pharmacy, Harbin University of Commerce, Harbin 150076, China;Anhui Jiren Pharmaceutical Co., Ltd., Bozhou 236800, China;Anhui Jiren Pharmaceutical Co., Ltd., Bozhou 236800, China;Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China |
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| Abstract: | Objective To establish an HPLC fingerprint method of Verbenae officinalis L. and determine the contents of its main components. Methods Many batches of Verbenae officinalis fingerprint and the contents of main components were determined by HPLC, and the similarity and cluster analysis of the fingerprints of each batch were compared and the contents of the main components were compared. Results The results showed that the difference of the main content of medicinal materials and fingerprints were between each batch of Verbenae officinalis. Conclusion The fingerprint and its main components determination method have been established to provide the scientific basis for the quality evaluation of Verbenae officinalis. |
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| Keywords: | Verbena officinalis L HPLC fingerprint Shufeng Jiedu Capsule index components |
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