腹水中乙型、丙型及庚型肝炎病毒的联合检测

观察小剂量血脂康、普伐他汀对高血脂病人的长期调脂作用。方法：多中心，１９５例高血脂病人，分血脂康组［每晚睡前口服血脂康２粒（含他汀类物质６ｍｇ）］与普伐他汀组（每晚睡前口服５ｍｇ）治疗６个月，比较治疗前、后血脂水平变化及两组间差异，用方差分析法检验及ｘ２检验。结果：血脂康与普伐他汀治疗６个月时，ＴＣ下降１６％及１７％，ＴＧ下降１３％及１５％，ＬＤＬ下降２３％及２１％；ＨＤＬ在血脂康组上升２％，在普伐他汀组上升１０ ％。两组均能有效降低 ＬＤＬ／ＨＤＬ。两组间比较普伐他汀升 ＨＤＬ作用较血脂康稍好（ Ｐ＝ ０．０５）。两组 ＴＣ、ＬＤＬ、ＬＤＬ／ＨＤＬ下降均有统计学意义。两组 ＴＧ下降及 ＨＤＬ升高无统计学意义，血脂康及普伐他汀组降 ＴＣ疗效分别为 ５４． ６％、 ６８． ４％；升 ＨＤＬ疗效分别为 ４９．１％、５３． ９ ％；降 ＴＧ为 ４６．２ ％、４０． ８ ％。两组疗效差异均无显著性。两组均未见严重副作用。结论：小剂量他汀类药物（如血脂康和普伐他汀）长期口服治疗成人血脂紊乱安全、有效。

Detection of HBV DNA, HCV RNA and HGV RNA in ascites

Objective: In order to study the infection of hepatitis B virus (HBV), hepatitis C virus(HCV) and hepatitis G virus (HGV) in ascites. Three kinds of virus in patients' serum and asciteswere detected, who suffered from cirrhosis and blood trans fusion usually. Methods: Polymerase chainreaction was used. Results: In serum and ascites of 32 patients, HBV DNA positive patients were 15(15/32) cases and 11(11/32 ) cases respectively, 7 (7/32) cases for HCV RNA, 10 (10/32) casesand 9 (9/32) cases for HGV RNA. The coincidences of serum and ascites for HBV, HCV, and HGVwere 73%, 100% and 90% respectively. 25 percent patients had overlapping infection of HBV andHGV in serum, 19% overlapping rate in ascites. 16 % to 12 % patients could detected HCV and HBVin serum and ascites simultaneously. Overlapping infection rates of three virus were 13 %. Conclusion:HBV DNA, HCV RNA and HGV RNA in ascites of patients could be detected who had virus inserum. Ascites had infectious specialty.