尿路感染病原菌的分布及耐药性分析

目的了解尿路感染病原菌的分布及耐药性,为临床提供可靠的诊断和治疗依据. 方法对1999年1月～2003年1月间,我院住院及门诊患者尿培养分离出的107株细菌进行鉴定和耐药分析. 结果尿路感染菌株以大肠埃希菌为主,占57.9%;其次为肠球菌属、变形菌属、肺炎克雷伯菌、铜绿假单胞菌、葡萄球菌属及真菌;肠杆菌科细菌除对亚胺培南保持100%敏感外,对其他抗生素耐药率均呈上升趋势;革兰阳性球菌耐药率也相当严重,仅万古霉素对革兰阳性球菌敏感率为100%. 结论尿路感染主要病原菌为肠杆菌科细菌,由于病原菌耐药性呈上升趋势,临床医师应根据尿培养结果合理使用抗菌药物.

Distribution and Resistance Status in Urinary System Infections

OBJECTIVE To determine the bacterial distribution and resistance status in urinary system infections. METHODS A total of 107 strains collected from inpatient and outpatient urine specimens during Jan 1999-Jan 2003 were identified and the drug resistance test was performed. RESULTS Escherichia coli rated the top one (57.9%), followed with Enterococcus, Proteus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus and fungi. Enterobacteriaceae were showed increasing drug resistance trend, but still sensitive to imipenem (100%). G -cocci were also showed serious drug resistance trend, but still sensitive to vancomycin (100%). CONCLUSIONS Enterobacteriaceae were the main infectious bacteria in urinary infection. Rational use of antibiotics should be carried out according to urine culture result.