| 狗肝菜化学成分研究 |
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| 引用本文： | 邹忠杰,崔红花,于治成,沈志滨.狗肝菜化学成分研究[J].中成药,2012,34(7):1309-1311. |
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| 作者姓名： | 邹忠杰 崔红花 于治成 沈志滨 |
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| 作者单位： | 广东药学院中药学院 |
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| 基金项目： | 科技部“十二五”重大新药创制(2011ZX09102-007-03);广东省教育厅高层次人才资助项目(2010);广东省科技计划项目(2010B030700044、2011A030100013) |
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| 摘 要： | 目的研究狗肝菜的化学成分。方法对狗肝菜全草95%乙醇提取物的三氯甲烷萃取部分利用反复硅胶柱层析和Sephadex LH-20凝胶层析进行分离,根据光谱数据和理化性质确定各化合物的结构。结果分离并鉴定了8个化合物,分别为正十八烷醇(1),乌苏酸(2),7-羟基香豆素(3),异土木香内酯(4),齐墩果酸(5),滨蒿内酯(6),薯蓣皂苷元(7)和β-谷甾醇(8)。结论化合物2、3、4、6和7为首次从该植物中分离得到。
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| 关 键 词： | 狗肝菜 化学成分 结构鉴定 |
Chemical constituents of Dicliptera chinensis(L.) Nees |
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| ZOU Zhong-jie,CUI Hong-hua,YU Zhi-cheng,SHEN Zhi-bin.Chemical constituents of Dicliptera chinensis(L.) Nees[J].Chinese Traditional Patent Medicine,2012,34(7):1309-1311. |
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| Authors: | ZOU Zhong-jie CUI Hong-hua YU Zhi-cheng SHEN Zhi-bin |
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| Institution: | (Guangdong Pharmaceutical University,Guangzhou 510006,China) |
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| Abstract: | AIM To investigate the chemical constituents of Dicliptera chinensis(L.) Nees.METHODS The constituents of chloroform-soluble portion of 95% ethanol extract were isolated and purified by means of repeated silica gel and Sephadex LH-20 chromatography.Compounds were identified by their physical characteristics and spectral features.RESULTS Eight compounds were isolated and identified as 1-octadecanol(1),ursolic acid(2),7-hydroxycoumarin(3),isoalantolactone(4),oleanic acid(5),scoparone(6),diosgenin(7) and β-stitosterol(8).CONCLUSION Compounds 2,3,4,6 and 7 were isolated from this plant for the first time. |
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| Keywords: | Dicliptera chinensis(L ) Nees chemical constituents structure identification |
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